Pulmonary embolism meds - liver risk?

FormerMember
FormerMember
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Hi I have stage 4 lung cancer and I was started on Xarelto (Rivaroxaban) on Sep 3rd for a PE.

In the last couple of weeks I've been getting what I think is liver pain. My consultant thinks it's deferred pain from a tumour in my right hand kidney. However, I've no obvious kidney pain but definitely pain in my liver region under my right hand ribs.

Having researched this on the web if seems that if you're unlucky you can get liver damage from blood thinners, including Xarelto.

I'm going to speak to my MacMillan nurse tomorrow about it but anyone got experience of this?

  • Hi Gary P.  I’ve not heard of anyone here with liver damage whilst on blood thinners. I think it is a good idea to talk to your Macmillan nurse, but have you had any recent blood tests? That would show if any real liver concerns. Also look out for yellowing of skin, and eyes. I’m not a nurse, so please only take this as my own general opinion. 

    “Try to be a rainbow, in somebody else's cloud” ~ Maya Angelou
    Chelle 

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  • FormerMember
    FormerMember in reply to chellesimo

    Last blood test was a few weeks ago but not sure it's designed to show liver function. It was just prior to some dental work. Prior to that it would be about 5 weeks since having the previous test before my immunotherapy

  • I’ve had PE, but I was on Clexane. I’ve done a general search of the site for Rivaroxaban and liver damage, but I couldn’t find anyone who has commented on this , sorry. 

    “Try to be a rainbow, in somebody else's cloud” ~ Maya Angelou
    Chelle 

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  • FormerMember
    FormerMember in reply to chellesimo

    Thanks. There are a few sites on Google linking Rivaroxaban with liver damage. It's not talked about by the maker.

  • FormerMember
    FormerMember in reply to chellesimo

    Just got my liver function tests back and all is normal apparently. I have a consultation on Weds so will find out more then

  • Hi Gary, well that is good news. I did wonder if it was gallbladder pain you were feeling, but as this is linked to the liver, I don’t know if this would show up in the liver function test. My other half had stones in his gallbladder and was in terrible pain, under the right side of his ribs. Good luck with the consultation on Wednesday. Let us know how you get on. 

    “Try to be a rainbow, in somebody else's cloud” ~ Maya Angelou
    Chelle 

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  • FormerMember
    FormerMember in reply to chellesimo

    Yes I wondered the same but there is no history of this and no indication of it on my last CT scan about a month ago. I will certainly let you know what's the result on Weds.

  • FormerMember
    FormerMember in reply to chellesimo

    I had a call from my consultant Monday afternoon. The news is not great I'm afraid.
    My cancer is spreading rapidly. It's now in my adrenal gland, bones, new spots in both lungs and my brain, specifically my cerebellum. I will be having an MRI to determine how advanced it is in my brain very soon.
    I have not responded well to immunotherapy and, as such, will be returning to aggressive Docetaxel chemotherapy from Jan 6th plus potential stereotactic radiosurgery on my brain at the Marsden ASAP.
    It's not good news and certainly not what any of us wanted to hear before Xmas. However, I'd rather know.
    My prognosis is 6 months with treatment. It's now up to me to decide on how I proceed. Not sure yet what's best to do.

  • Hi Gary, I am so terribly sorry to hear this. That is indeed a huge decision for you to make. Do you have support at home? I would urge you to call the Macmillan support line where you can talk this through with someone, I think it will give you the help you need to make this decision. They are open 7 days a week from 8am til 8pm on 0808 808 00 00. I wish you all the very best Gary. 

    “Try to be a rainbow, in somebody else's cloud” ~ Maya Angelou
    Chelle 

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  • FormerMember
    FormerMember in reply to chellesimo

    Thanks for the info. I'm lucky to have a great wife who is looking after me and a Macmillan nurse I have spoken to today. I appreciate your concern.