Nice approved PHESGO last week and I had my first subcutaneous injection today . Only have 4 more to go now and treatment finished . Assume any side effects will be similar to previous IV doses but interested to hear if anybody else having it
Hi Northerner - good advice re pre-warming but would take a while to warm it up though as it’s 10ml and I think Herceptin is 5ml? The guidance is to inject it over 5 minutes which they do. Only the first few mls that sting - after that it’s OK . Had my second yesterday and was OK . Only 3 to go and then the year of Herceptin and Perjeta is finished !
best wishes
Hi Carlo41
It’s amazing how well you will feel not having the docetaxel, I’m so pleased it’s your last one, you will realise how brave you’ve been in a few weeks and the docetaxel will be a distant memory. You can make it through this next couple of weeks then tackle the next step!
I definitely hit the chemo wall like you but have felt much better since not having the docetaxel, I’ve got surgery next week and then T & P will start again 2 weeks after that.
Sending positive thoughts for your journey ahead xxx
I am pleased to hear this Pineapple21.
I had my last round of Docetaxel with Pertuzamab and trastuzamab just over a week ago and my side effects from changing drugs from EC to the above have been much more unpleasant.
As far as I am aware I should continue with the T and P for another 15 3 weekly sessions. I thought they would be via IV but my nurse at my last session said they are going to be given by injection. I need to clarify this with my oncologist as I thought they might have let me know!
It's difficult to know which drugs are causing the side effects when you are having 3 different ones at the same time, as well as Filgisfrim injections which I only started with the Docetaxel. I'm hoping I don't need to continue with those now the Docetaxel has finished. Another thing to clarify with my oncologist.
I'm waiting to hear about my surgery now. Thought I might have heard but perhaps they are waiting to see what my MRI shows up on Monday
Moppers:
Have you been having the Herceptin combo for the full year (via IV then final 4 subcutaneously) or have you just had 4 lots of Herceptin?
Julie x x x
Hi Eiluj, Yes I am finishing the year of Her/Per, having had the majority IV . My oncologist switched me to Phesgo as soon as it became available so the last 5 will be subcutaneous.
Sounds as if you are getting through things and you won’t be needing to continue with Filgrastim - something to celebrate!
Best wishes re your surgery
Thanks Pineapple21 great to hear this and feel ive Climbed that wall and your kind words help xx
Good Luck with your surgery next week and wishing you a speedy recovery.
Take care. xx
Hi
i have finished the chemo in January and I am still having the pertuzamab and trastuzumab in 3 weekly cycles until November. Just wondering if you or anyone has side affects on these?
I suffer from really aching bones in my legs and hips. Some days I am okay but some days I walk like I am 20 years older. I thought I would start to feel better after the chemo but sometimes I feel awful.
best wishes all x
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2025 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007