Unexpected parent loss & cancer of an unknown primary

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Hi everyone,

I can’t quite believe I am writing this. I wanted to share my mum’s journey.

On 9th February, my mum became suddenly unwell with what was thought to be an infection. She was blue-lighted to hospital, started on broad-spectrum antibiotics, and sent for a CT scan. At around 3am, we were told that she had sepsis caused by a blocked kidney, but the scan had also revealed widespread metastatic cancer in her peritoneum, liver, and possibly lungs.

Her condition deteriorated quickly and she was placed in an induced coma on 10th February and admitted to ICU.

I won’t go into all the details, but our ICU experience was very difficult. Communication was often poor and consultants rotated frequently, which made it hard to get consistent information. There was also a failed biopsy, which delayed a confirmed diagnosis, while intermittent CT scans during this time showed very aggressive progression of the disease. By the second week, despite still not having a confirmed primary cancer diagnosis, end-of-life discussions had already begun.

Unfortunately, we were never able to wake my mum. Whenever sedation was reduced she became extremely agitated, which doctors believed could have been due to delirium, metabolic/toxic effects of the cancer, or possible involvement of small brain structures. A head MRI was never performed, so we never received a clear explanation.

When we finally received a pathology result, it showed poorly differentiated adenocarcinoma, most likely ovarian or upper GI/hepatobiliary in origin, but it was never confirmed. Her official cause of death is recorded as metastatic cancer of unknown primary with sepsis.

My mum died on 8th March, with my brother and I sleeping beside her in her arms.

Looking back, we realise that she had been experiencing groin/ abdominal pain, recurrent UTIs, intermittent nausea and episodes of vomiting, which in hindsight may have been early symptoms of the cancer. Other than this she was fit, well and in her prime at 61 years old Sob

The entire course — from hospital admission with sepsis to her passing — was incredibly rapid.

I think what I’m feeling most is disbelief. It all happened so quickly that it still feels unreal. If anyone has experienced something similar, I would really appreciate hearing from you.

Thank you for reading

  • Hi antypim. Im sorry to read about your mum and how sudden things happened. You will be in shock, upset, anxious and a whole load of other feelings. Im glad you had your brother with you. 

    I dont have experience of this cancer but my husband, who died in October, had 2 episodes in ICU, ventilator and pneumonia then the ups and downs of failed chemo and radiotherapy. 

    There may be others here who will pop by to say hello, people are very supportive here.

    These early days and weeks can pass by in a blur, paperwork to do, funeral, telling people, its exhausting. Allow yourself to cry and do whatever you need to get through each minute, hour and day. In my case it was a lot of rubbish telly, something I still do. 

    One massive hug coming your way. 

  • Hello, a lot of what you have written is sadly very familiar to me, i am so, so sorry this has happened to your mum and your family. My Mum was diagnosed in july 2024, the diagnosis went very quickly from what we were told was a blood clot to stage 3 squamous cell carcinoma. long story as short as i can, she had treatment, did not respond very well, cancer spread to her spine, but overall, given how ill she was she was doing ok...until 2 jan this year, when she could not stop shaking and was blue lighted to hospital, where they found her lung had collapsed and that she had pneumonia. they treated her but she did not respond, she was moved to an acute respiratory ward where we were told end of life was near, we spent 2 weeks practically living at the hospital, seeing a different consultant every few days and they all having different views, some saying the spread seen on the scans was infection, some saying the cancer had become very aggressive and watching our mother decline in a way i never thought possible, the last few days she was very agitated every time she woke up, which was incredibly distressing, they just kept upping her meds, until we watched her take her last breath.  It was the worst 2 weeks of my whole life, for so many reasons, and as well as struggling with the loss i am struggling with what happened in hospital too, i really do emapathise with you, we really thought, and so did the doctors, that she had more time, she was due to start immunotherapy the day after she was rushed in, the irony of that is so painful to me i cant tell you. take care of yourself, its a painful place to be, i know x

  • Hello,

    I am so sorry for your loss and your mums story is so similar.

    like you we had a different consultant everyday on the ICU- the messaging varied wildly and had us false hope (I am a scientist by background and so I knew where were in a bed place to start) even up until a couple days before her diagnosis. 

    I am sure you are still struggling as it is so fresh. But I guess am having a hard time believing it all - did you find the same?

  • So sorry to hear about your husband. Sounds like you guys really went through it.

    Thank you for your kind supportive words. I can literally manage one task a day. Today was meet the pathologist who will do mums post mortem. I’ve started a new series which mum would have liked which helps, and am signed off work. But the days are long and painful. I doubt that’s ever going to change Disappointed 

  • Hello, i hope you are coping, its so hard. Yes, i did feel the same and still do, i still feel sometimes like none of it could be real, she cant be gone! and everything that happened in hospital, was so messed up, it was not how i thought the end would be, not at all, and that does not help with the processing. I have spoken to cruse and they were really helpful. When i was 19, i lost my Dad to cancer as well, he was only 40.  He went to the gp with a cough, was put on antibiotics, they did not work so was sent for a scan, and they found cancer throughout his entire lymphatic system, he was admitted to hospital, sedated and died 3 weeks later, undifferentiated carcinoma. The sudden nature of his death was extremely traumatic, so i know what you are going through on several levels and its huge, im not going to cliche you, that did (and still does!) do my head in, i just want you to know i understand what you are going through, what you are feeling is normal for what you have been through, at least i hope it is, because its how i feel too. Please take care of yourself.