Darolutamide

Good morning all,

I've been on darolutamide for 1 year 9 months as part of triplet therapy.

Last Thursday evening I experienced what I think was a migraine (never had one of these before so not 100% sure). It involved a severe headache and painful eyes, occurred around 10.30pm, so I took paracetomol and went to bed. Following morning the headache had gone but was followed by weird visual disturbances including:

• slightly blurry close vision - distance clear.
• partial patchy sight loss in far left field.
• seeing faint images both still and moving for 10 minutes or so after I'd already seen them. These appeared over the top of normal vision.
• three brief instances of double vision, just a few minutes each time.
• and this was the weirdest - watching a film on TV there was a character with a very distinctive face and all the other characters - plus my wife - started to look similar for a while!

This carried on through Friday, got worse Saturday (when the double vision occurred), improved significantly by Sunday and was completely gone and back to normal yesterday. Still normal today. I reported to oncology Saturday morning and was told to stop dariolutamide which I have. I have appointments in the hospital eye clinic Thursday and my consultant has been informed.

Has anyone experienced anything similar or know anyone who has? Any info / ideas welcome.

Derek.