PSA rise

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Hi All. My husband was diagnosed with stage 4b in January 2025 and he had triplet therapy last year (and ongoing hormone treatment and darolutimide). 

My husband’s PSA started rising a few months ago and a PSMA PET scan showed one (possibly two) areas of activity. He had radiotherapy on those spots 4 weeks ago and we just had a PSA test which has gone up slightly from the last time (4 weeks ago). Has anyone else had this? Would it take a while for the radiotherapy to actually bring the PSA down? Thanks in advance