3mm apical positive margin

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Hi,

I’m currently 4 months post RP.

Continence fully back to normal. ED an issue.

My biggest concern is that they found a greater than 3mm positive margin after pathology looked at the removed prostate.

MARGIN STATUS - POSITIVE

EXTENT (TOTAL) - GREATER THAN 3MM

LOCATION - APEX

LYMPHOVASCULAR INVASION  - NOT IDENTIFIED

INVASIVE CRIBRIFORM AND/OR INTRADUCTAL - NOT IDENTIFIED. 


Consultant’s letter after six weeks check:

“ We had long discussions about the apical margin positivity. I have explained that the prostate is deficient of capsule at the apex but it is an area that he had a primary disease. All that can be done at the moment is to monitor the PSA. If it rises above 0.2, he will require a PSMA PET scan to decide if he could benefit from adjuvant radiotherapy. For the time being, I have reassured him that his PSA is where we expect it to be”.

How concerned should I be about this PSM?

Will I need further treatment?

Your thoughts please.

Thank you

  • Hello Andy ( 

    Thanks for the post. Your team are on your case - they are aware that there are positive margins from the histology once they had your prostate on the lab bench under the microscope.

    I assume that you will now be on 3 monthly PSA tests. IF any of the PSA tests show a rise to 0.2 or more your team are going to take action to find and kill of any remaining cancer cells.

    Yes you will need further treatment IF your PSA rises above 0.2 but you are being watched and any further treatment should still be on a "curative pathway".

    You are doing great to be continent at 4 months post surgery - the ED should slowly improve but if it doesn't your team can help in this department.

    Keep us posted as to how you get on.

    Best wishes - Brian.

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  • Hi  , sorry to hear that you are concerned.  I understand this to mean that cancer cells have been found near the edge of the capsule, which increases the risk that some may have escaped.  However, cells found near the Apex have better outcomes, so that’s why your team are suggesting close monitoring.  I personally would be watching my next PSA and if an increase found, would be questioning about starting Full RT rather than wait for a rise to 0.2.   I would then take the advice offered by them.  Please come back if you need anything more.

    Best wishes, David

    Please remember that I am not medically trained and the above are my personal views.

  • Thank you for your reply.

  • Hi Everyone,

    I’ve just received the result of my 3 monthly  PSA blood test taken yesterday:

    Your latest PSA result from 28th April remains undetectable at <0.1 so good news.

    This is good news. Another 3 months without any worry. 

    Though  the ‘greater than 3mm positive margin’ remains a concern to me.

    Andy

  • Hello Andy ( 

    Thank you for the update and the good news.

    Another 3 months without any worry. 

    You are spot on - enjoy the next 3 months and try and put "PSA and Margins" to the back of your mind - enjoy life, the sun's shining.

    Best wishes - Brian.

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