Hormone Therapy - Relugolix Side Effects

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Diagnosed with Pca in November 2024.

Gleason 4 + 3 - Locally advanced.

Started HT in January 2025 - Prescribed Relugolix Tablets.

RT completed June 2025.

Possible Side Effects of Relugolix:

Very painful finger joints both hands, with chronic stiffness, claw like appearance, mimics rheumatoid arthritis.

Both eyes sore and dry, double vision

Cardiac - AFib and palpitations.

My subsequent research reveals that side effects of HD may include the above symptoms.

Would welcome any comments and or experiences.

  • Hi  , I noticed nobody had replied so my reply will bump you back up the list.  These are all side effects but I think you would be very unlucky to have them all as a result of treatment although I guess not impossible.  I always immediately jump to the conclusion with any ache or pain that it is PCa related, but most of the time things are age related in my case.  Just make sure that your team and/or GP are aware of any symptoms. 

    Best wishes, David

    Please remember that I am not medically trained and the above are my personal views.

  • Most of us are at an age where stuff starts dropping off anyway, so there is a temptation to blame these unfortunate side effects of not dying on the cancer.

    When you have Cancer it can be difficult to understand that you can have other problems as well.

    We become so fixated on the cancer that all else pales into insignificance.

    It's a thing to watch for.

    Back problems are just as painful if they are not caused by Cancer, I can tell you.

    Steve

    Changed, but not diminished.