There have been a couple of headlines on new drugs over the weekend, one for breast cancer and the other for neck and head cancer. My ears picked up because one of them had been mentioned by our oncologist. Looking into them I discovered that they are both being trialed for prostate cancer patients with varying degrees of success but it is reassuring that there is so much work going on in the background to develop new treatments and protocols particularly for newly diagnosed men.
Pembrolizumab is the other one but there is an interesting article on immunotherapy which is proving to be difficult for prostate cancer patients.
https://www.cancertherapyadvisor.com/features/immunotherapy-for-prostate-cancer/
Hello Alwayshope
Thank you for posting the above, interesting reading and I hope soon to be as you would say "more tools in the toolbox".
Kind Regards - Brian.
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Hi !
You always find interesting stuff on new trials and studies on treatments and I thought I could share some interesting facts now in the radioligand therapy.
Most think of Pluvicto, Lutetium and lots of other very interesting isotopes used and upcoming (Actinium, Copper and etc,)
What is interesting is new ’tracers’, not targeting PSMA but also other proteins overexpressed on prostate cancer and there are actually trials and studies in this area that looks very promising. Here is one example:
I really belive in the immunotherapy field even if it seems more difficult to find antibodies and / or CAR-T with the power to activate the immune system to attack ’cold tumors’ like prostate cancer. But, radioligand therapy is a very good pathway, using efficient ’tracers’ to hunt down prostate cancer cells and then attacking them with radioactive isotopes
Like I said Alwayshope, it’s always nice to follow when you start new threads or add your knowledge to existing threads 
Hi !
Found a new trial. Still early stage of course but now in the immunotherapy field and with bispecific antibodies and not actually the overexpression of PSMA 
As my wife have a blood cancer diagnos (multiple myeloma) I have really been into looking at the immunotherapy research there because blood cancers, compared to many other sorts of cancer have come a long way in using immunotherapy as treatment because most blood cancer responds very well to these types of treatments and in many ways those cancer are actually moving from being only not curable and basically deadly to a more cronic disease state.
Anyway, big hopes in the future for prostate cancer as well with new forms of immunotherapies coming up
Hi !
She was diagnosed in 2014 and she is still kicking 
Lots of different treatments and in her case she hasn’t had the big game changer; CAR-T therapy which have proven remarkable results in multiple myeloma 
Yes, there are many cancer areas with up and coming immunotherapy treatment. I think the biggest challenge with cold tumors like prostate cancer is to really be able to mobilize T-cells to the extenthat you can really penetrate into the tumors. But time will tell 
In the mean time I’m also thinking radioligand therapy is a very promising area with more isoptopes, new tracers, earlier use of it. I think it’s a little bit like treating with bispecific antibodieexcept that, instead of mobilizing T cells you drop a payload of radiation
The biggest problems with new cutting edge treatments is the price tag and already you see public healthcare saying no to treatments that will have big impact. Cancer doesn’t come in one form…. 
