Tinnitus after Carboplatin

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Hi,

I'm currently undergoing treatment for tonsil cancer - T2N1M0.  Treatment plan is 6 weeks radiotherapy and 2 cycles of chemotherapy.  Due to pre-existing mild tinnitus the chemo is Carboplatin at 5AUC weeks 1 and weeks 5. I'm currently at the start of week 5 of treatment.

About 3 days after the first chemo cycle I developed a spike in my tinnitus which has persisted for the last 28 days. Maybe about a 20% increase from baseline, making it much more intrusive.  My single lymph node has resonded well to treatment so far, shrinking between 50-75%.  I discussed with my oncologist and he said due to tinnitus and good response I could either omit the 2nd dose, or go for a reduced AUC 2.5 dose.

I arranged for the reduced dose for cycle 2, but then when I went yesterday (26th march) I got quite stressed about the possiblity of the tinnitus worsening and I didn't go through with the cycle.  Now i'm a bit stressed about having missed that 2nd cycle - although I think the benefit of it is quite marginal. Maybe 6-8% for chemo overall, with most of that in the 1st dose. So maybe the benefit of the reduced 2nd dose might be 1-3%?  I feel like i'm being a bit flippant with the cancer - but the tinnitus is quite impactful day to day and I really don't want it to get any worse than it is now.

Just wondered if anyone else missed the 2nd dose due to toxicity issues - or if people have experiences of tinnitus after chemo and whether it lasted or went away?

Thanks

  • Just wondered if anyone else missed the 2nd dose

    Hi. Don’t stress. Lots of people miss that second dose. 
    I know Hazel missed one out of three. Percentage wise it makes very little difference whereas tinnitus is a major side effect to put up with. 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

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