Depressed and Anxious

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Hi,

I’m new here, and I’ve come to basically find out if I am alone in how I’m feeling since a total thyroidectomy in January, and starting Levothyroxine (125mg).

I had radioactive iodine treatment in May, and I am now classed as ‘low risk’.

I have struggled with anxiety in the past, but since surgery and starting Levothyroxine, I am a shadow of myself. I am anxious all the time, which in turn makes me feel depressed, and I feel like I’m pushing my partner away, and can’t seem to shake it.

I’ve been to my GP, had blood tests which have come back that my TSH is ‘normal’, and the GP suggested increasing my dosage, but this would mean increase risk of cancer again, increased heart rate, and increased in anxiousness. So I declined, and I’m still now confused why it was even suggested to increase it?

I’m self referred to talking therapy and on the waiting list, I’ve tried CBT, which didn’t work. I’ve been offered antidepressants, but I am skeptical. 

Has anyone else felt like this after surgery and starting the Levothyroxine, has anyone fixed it? Is there something else I should be asking the GP to check? I was ok before all this, and I feel like it’s got to be connected in some way.

Thanks for reading if anyone is out there..

  • Hi  and a very warm welcome to the online community which I hope you'll find is both an informative and supportive place to be.

    I’m Anne, one of the Community Champions here on the Online Community and, although I'm not a member of this group, I noticed that your post hadn't had any replies yet. Responding to you will 'bump' it back to the top of the discussion list again.

    I hope you don't have to wait too long for the talking therapy.

    ((hugs))

    Community Champion Badge

     "Never regret a day in your life, good days give you happiness, bad days give you experience"

  • Hi

    I totally understand how you feel. I had Radioactive Iodine in July this year and also classed as low risk. Nevertheless I  have felt quite low. I started taking Thyroxine back in January 2025. I have been seeing a Counsellor for the last eight weeks. Some days are definitely harder than others. Also sometimes sorting out Thyroxine doses takes time. I have also rung the nurses and a couple of times and they have been very helpful. I have quite often said to my husband that it would be nice to be like I was before. Some days I am fine and then some days I am not but hopefully the good ones will outweigh the not so good. Be kind to yourself. If there is anything you would like to ask me, please do. 

    Sue x

  • Hi there,

    I had RAI in October 2023 and am currently on a daily dose of 125mcg Levothyroxine having asked my specialist earlier this year if I could reduce my dose from 150mcg as I'd noticed that on the higher dose that I was definitely more prone to anxiety than I had ever been before in my life. The specialist agreed to lowering my dose as an experiment  at first because my blood results were stable enough and I'm glad to say that my bloods have remained stable and I feel much calmer and more like my usual self now and hope to stay on  the 125mcg dose.

    I've read quite a few posts on here over the last couple of years with people mentioning experiencing issues with low mood and anxiety when taking Levothyroxine so you're not alone. Also, you've been through a difficult time and your body is adjusting to the change of being on Levothyroxine tablets now that you don't have your own thyroid any more. I think my body is stiill adjusting to all that too.

    This is a very supportive forum so do feel free to come on here and chat and ask any other questions you may have.