Recently my wife diagnosed with Minimally invasive Follicular cancer with capsular invasion (3 Foci) and Vascular invasion (2 foci). As per the biopsy report from the left thyroidectomy, it seems there is no extra thyroid extension and Mitotic rate is low. I believe these two points are good sign. Please note, she had 4.5cmm lump.
last week, she had her full Thyroidectomy and now we are waiting for next biopsy report form the TT and then, RAI.
i have been following this forum for last couple of days and find it very useful. Hence, thought of asking these questions? Appreciate if anyone can shade some light on these points?
1) Vascular invasion: it’s a area of concern. how many foci is to be considered as high risk and/or widely invasive
2) has anyone sees a massive change of biopsy report after the full TT?
3) Follicular has a tendency to spread ... as it’s minimally invasive and Mitotic rate is low, does it mean it has less chance of metastasis?
4) how important is Cancer margin? My wife’s one is 0.7mm from the margin. Is it good or bad? What are the criteria of this margin to be low and/or high risk.
I wish you all the best. Take care.
Hello
It's natural to be concerned about the details, but can I please ask you not to get bogged down in how many foci etc. The treatment will be pretty much the same regardless and your wife's medical team are the people best placed to tell you what the risk is for her particular case.
My lump was a lot bigger than your wife's - 7cm or more - and it was minimally invasive on both capsular and vascular. 11 years after diagnosis, everything went smoothly.and I've had no problems since my thyroid was removed and the RAI was completed.
The Multi Disciplinary Team (if you're in the UK, that's what it's called - if elsewhere, I'd expect something similar) will assess your wife's case and make decisions on what happens next, and how they see the risk factors. In Thyroid cancer, in the UK, we're not much hung up on staging - mostly because thyroid cancer is pretty rare (so the statistics aren't so robust) and because treatment is very similar regardless of stage.
You say 'follicular has a tendency to spread'. That's potentially misleading. The different in risk between the more common papillary and the follicular variants is not so different. When they do spread, they tend to spread to different places, but you shouldn't be worrying that follicular is intrinsically significantly more dangerous.
Please, pick up your detailed questions with the doctors.
Best wishes
Barbara
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