Shock diagnosis after annual GP MOT

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Hi everyone

My OH received news in March 25 that his annual MOT at the GP showed a PSA of 77

We were 'gobsmacked' as he hadn't had any issues at all but suddenly our world turned to chaos and within 5 weeks he had had a CT, Biopsy, MRI and had 2 Urology appointments.

His Gleason was 4+ 3 =7 , T3, N0, M0

They put him in CPG 5.Locally advanced

All this sounded so bad to us, but the Urologist was  confident it was curative and would start Hormone Treatment straight away, followed by Radiotherapy

He started Bicalutimide tablets on 18th June and had his 1st Hormone injection on 2nd July

Met the Oncologist today and Radiotherapy will start in mid  October for 4 weeks, 5 days a week.

I must say that all medical staff have been absolutely brilliant but one thing we would like to know from people who have gone through this Treatment.

Consultants have given us a list of side effects he might have on Hormone Treatment but fingers crossed, after 5 weeks he has had nothing at all. 

  • Is this normal or is this yet to happen.
  • If so how long before he may see any of these side effects 

Thanks 

  • Dear  

    you certainly know how to give everyone in this forum perspective & hope .

    hugsst hugs to you both. 

    liz & OH 

  • Sorry to hear of your OH’s diagnosis @Cal58 and yes, your world does head off in another direction for a while.

    If it helps, I started Zoladex LA therapy late last year and for the first two three-monthly injections I thought I’d got away with almost no side-effects. After the third, the hot flushes became more often and more pronounced, but only last for a minute or so. Some days I get more than others and sometimes I wake in the night due to hot flushes and have to cool off. They are very manageable.

    My memory for names and dates seems to have dipped too although that was never one of my strong points anyway...!  I was told these side-effects are quite normal.

    I have just finished the four weeks of weekday radiation treatment your OH will be starting in October, after 8 months on Zoladex. 

    Wishing you both the best of luck with your journey through this.

  • Thank you. Hearing others relate their experiences is really helpful. OH has starting feeling fatigued over the last few days and his Gout has flared so I guess this is all part of the side effects. Best wishes 

    • Hi interesting that your OH gout has flared.   You can see from OH bio that he has had problems with his feet since commencing his salvage treatment which included RT and HT.  Although the tests for gout came back negative he has had all the symptoms and is convinced it  connected to the HT.  As he has completed his salvage RT and his PSA is right down he has stopped the HT with the agreement of his oncologist and his feet are getting better.  I hope all goes OK with your OH treatment my OH sailed through the RT with hardly any side effects.
  •  you have sparked my interest now with those comments. Since my HT & RT my right foot and both thumbs have become painful. I've attributed this to arthritis but maybe the treatment has had some effect on these joints. 
    My last three month HT implant was October 2024 but the side effects are still very present. Time alone will tell.

    Rod

  • Certainly looks like your pathway will lead to a cure, it won’t be all easy but a great job is getting started, we are all different and respond in different ways so it’s difficult to say just how it will go in your case. Earlier on during my Ht I had quite a few hot sweats but these have become less as I have continued these days I have more problems with shoulder and muscle pain and some swelling in my feet and lower legs!!Just hope you don’t get to much of anything on my last treatment now yippee just remember it Is doing a great job! Very Best Wishes David