Treatment for metastatic prostate cancer

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Hi everyone, I’m back..after my husband ended up in hospital for 3 weeks with kidney failure due to his prostate blocking his tube’s. He’s now much better after fitting stents in the kidney tubes, all working fine and kidneys are repairing well.

 
So he started hormone treatments and he’s feeling tired but generally good, eating again and all ok.  

He’s having zodalex shots every 3 months, we have now been asked to decide what treatment to have to prolong the zodalex lifespan, we’re told that after 18months or so they are likely to no longer work, his cancer will become resistant to it..he’s been offered chemo with darolutamide and doxetaxel, the side effects sound dreadful (if he gets them I know) but this treatment will be over 6 months and apparently it will extend the life of the drug for about the same length of time! Which seems pointless to us, or he can try enzalutamide instead of chemo..we don’t know if this is a better option or not.

anyone have any experience with either options? They have told us that should the zodalex stop working they can probably do chemo then!  

we can’t help thinking that 6 months of chemo now whilst he’s feeling healthy would be a waste of his precious time, we were hoping to have a few breaks to make some memories as we have been constantly working for so long, not having holidays, we have a lot of thing we would like to do whilst he’s feeling ok 
would appreciate any feedback on the treatment options.

I know everyone’s journey is different and it will be up to my husband to decide, it’s all very overwhelming.

I hubby has a Gleason score of 9 PSA 46 (waiting for new test results) metastatic in lymph nodes only atm.   

thank you everyone 

  • Hi.  My husband was diagnosed and had a radical prostectomy in 2019.  Unfortunately it has spread to his bones since.  He has been on Zoladex for almost two years now and also Enzalutamide for over a year.  The side affects for him are hot flushes and some fatigue, but not too bad.  He is now looking to having plates put in his leg to strengthen his femur to prevent a break and he also has a collapsed vertabrae, which oncology is still unsure if it is the cancer or oestoporosis.  The drugs seem to work still for my husband to a degree, so we think well worth taking.

  • Thank you so much.  I do hope your husbands bone issues are solved, it’s so frightening not being able to help them isn’t it.  I appreciate you taking time to get back to me.

  • Hi Franypan just read your post, you do not mention that you spouse takes tablets to offset osteoporosis, because I'm on hormones tablets and injection I have osteoporosis and take Alendronic Acid and accrete D3.

  • No he doesn't take anything for osteoporosis at the moment.  We are at oncology tomorrow so might find out more then.  On the plus side just got issued a Blue Badge, which will definitely help matters!

  • If you're husband is under pension age he can also get a disabled bus pass, if he needs it ask Macmillan for a Macmillan toilet pass and a radar key I have both.