Treatment for metastatic prostate cancer

Tough decision. I did Lupron, docetaxel, and abiraterone simultaneously (PEACE 1 protocol). For me, side effects weren't bad, but everyone's different. Get info from your med team and make the decision that works for you.

i've been on abiraterone for 4yrs still working fine 

i would never have chemo again 

thanks for that x he doesnt fancy the chemo either

thank you 

Have they offered Enzalutamide - its another form of hormone therapy?  Like you husband I was diagnosed with metastatic PC back in 2021.  At that time (Covid) they offered Enzalutamide as a first line treatment instead of chemo as they were concerned about chemo patients catching covid.  I am not sure if this is still available but worth checking with your oncologist if you don't fancy chemo - I was certainly keen not to have chemo up front.  Touch wood, 2 years down the line the PC is very much at bay but the side-effects of hormone treatment (particularly the fatigue) have required a bit of a change of lifestyle.

Good luck for the future, stay strong, Steve

Thank you Steve, he has been offered enzalutomide as an option, our concern with that was the fatigue.  Do you still mange to be active with the fatigue, is it constant or does it hit you later in the day, I.e. can you mange holidays and perhaps an evening out?  Hope you don’t mind me asking, and I realise it may not be the same for my hubby, but the doctors aren’t the ones who are experiencing the side effects are they, so they can’t really tell us how it is.  If you can help, thank you so much for taking the time.

The fatigue isn't so limiting. I am still working, I am a software engineer so not too strenuous  but  about a year ago I did reduce my hours to 4 days a week as I did feel fairly wiped out by the end of the week.  We still go out of an evening although I will usually  follow it with a quieter day if its a late night.

Holidays are great - I really look forward to them.  Again we may not do quite as much and I don't think I could go back-packing!  We had 2 weeks in Cornwall last year and by the second week my energy levels had rebounded right back.  We are off to Italy for a couple of weeks soon and I am really looking forward to that, first trip abroad since Covid.

The slide-effects of these drugs seems to hit everyone slightly differently and it I think it may depend on how active you are, we try to go for a rapid 40 min walk every day at minimum, in addition to a run once a week (that used to be 3 times a week).

Hope this is helpful to you.  If your hubby starts on Enzalutamide but find it affects his quality of life too much he can always stop - he is in charge of what treatment he chooses to have.

Good luck with it Steve

Thank you so much Steve.  Really helpful.  Wishing you all the very best with everything you are going through, so kind of you to take the time to reply to us.

Hi Ravenfae , I'm stage 4 Gleason 9 and on enzalutamide 4 tables a day and decapeptal injection every 24 week's,yes there are side effects but I can live with that, was put on them straight away, iv also had RT which shrank the prostate. Chemo is next step if needed, I'm 2.5 year's in, also go to Maggie group two guys there with 11 years on enzalutamide, but we are all different, see what oncologist say after all they are the expert's 

Thank you so much