Darolutamide as add in to HT and docetaxil

Hi. Louli

I know what your saying, you always feel I want to know more, that if there’s three treatments that are simuler, are you on the best one, as we’re all different one may work better than the other.

The combination you have mentioned, would cause massive side effects, but food for thought. I have always maintained that using a dialysis machine then pumping chemo in would be productive but costly my opinion. Thanks for the heads up on your visit.

Stay safe

Joe

Thank you for the feed back Lou, I have added darolutamide to my list haha

Hi Louli

Hubby is mPSPC

• Adding Darolutamide to docetaxel and Hormone treatment to him at his stage is very beneficial.  As the trials were run on hormone sensitive and not hormone resistant prostate cancer.  When it becomes mHRPC this 3 pronged approach will not work, or at least not as well.  There is lots of info on it on the internet, just make sure you look at Doralumatide 2022 and not 2021 as two totally different trials.  We had an appointment with our oncologist and team yesterday who said this will be the standard of care in future for men with mHSPC, but it will not happen immediately and unfortunately unlikely to happen to my hubby as he is already had 3 cycles of docetaxel.  On a positive note they did say that maybe later on if hubby is still strong enough and he is still mHSPC that he could be given the 3 together.  We live in France.
• Ginny

Thank you Septimus fir your reply. It’s encouraging!

why is it not the standard of care now please??

kindcregards,

Louli x

Thank you for this. Its helpful to know that this drug could be on offer. I have a suspicion that I'm not responding to Enzalutamide as well as hoped so I will certainly raise this with my oncologist if the trend of a rising PSA continues. 

Hi sussex20 

did you have any radiotherapy as part of treatment? How high has the psa risen 

you could ask your oncologist for the drug Abiraterone that has been started for me if you think enzalutamide not helping 

Thanks Joe… yes it’s all looking good on paper but as you say to have been through so much it does make you think twice at the toll of it all. 
take care my friend…

Louli

Hi Paul,

…and the list just gets longer lol

i suppose that’s not too bad a thing …given our circumstances.

Best,

Louli

Yes Suss… always good to talk to an expert but I’m so sorry you feel you might not be responding as well as before. My husband is on Arbiterone and although he has only been in it for about 4 months and his PSA below 0.01 it’s always on the back of our minds that it might not last. How long do these work for anyway?? Does anyone know??

best,

Louli

It certainly isn't Lou x