Anyone at stage 4 had any experience of this regime? Clinical study shows a remarkable effect at stage 4 advanced metastatic prostate cancer. The triple pronged approach was found to reduce risk of death by 32% and a 65% increase in progression free survival and prolonged life by 4 years!!
It was approved for use in 2020 in NHS but I’m just wondering if anyone here has any experience of Darolutamide?
FYI the article was found in the Daily Mail on Sunday on Feb 27th ‘22 and was written by Ethan Ennals.
We are going to see the oncologist in a couple of weeks and as my lovely hubby is doing great on Zytiga and Prostap I want to know if he will be offered chemo and Darolutamide.
All the best,
from Louli
I think this is really positive . I will let you know what we are told but our situation is aggressive ductal adenocarcinoma with bone and lung mets. My lovely man is holding his own on Zytiga and Prostap so we are hoping this might offer us hope further down the line…
Ductal adenocarcinoma makes up less than 1% of all Prostate cancers.
regards,
Louli
I have found and read the article Lou and you are correct, it sounds very promising. Please let us know what your husbands consultant says, hopefully this will get the approval it needs and could be another treatment path for us advanced stage 4 patients. Glad to hear your husband is doing good, I hope you are also good. Take care
Regards
Paul
"Diagnosed March 2021 at 38 years old with stage 4 metastatic prostate cancer, my journey so far is on my profile"
Sorry for the late reply Paul… yes I have my moments… thank you for caring.. we are going to make a prioritised list of things to discuss with the oncologist on the 17th. I’m not looking forward to it in case they say no hope.
Sending much love to you and your family..
Louli
Great stuff! We have our next appointment this Friday with the oncologist. So if you could let us know what they think about Darolutamide in advanced PC.
kind Est regards,
louli x
Update everyone!
Hi Joeven, Paul82, Sussex20 et al….
So at our appointment with the oncologist today we asked about Darolutamide and we were advised that it was from the same group of drugs as Enzalutamide and Arbiterone which most of advanced PC patients are on or have been on for a while at least, most of whom have success in reducing PSA and staving off the disease.
As my husband’s disease is stable the dr appeared reluctant to discuss Darolutamide further than that. We felt a bit discouraged to ask for their clinical experience with it for now but it would’ve been interesting to know just the same.
it’s my opinion that if you are sitting there with advanced stage 4 PC which is no longer responding to one brand of hormone I would certainly be asking for a serious discussion about the efficacy of Darolutamide in combination with chemo and HT as per the article above.
I would be interested to know if anyone else has had a chance to ask their team about it yet??
Sending much love,
Louli xx
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