Hello everyone,
Has anyone experienced chest tightness/ difficulty breathing since being on Bicalutamide?
Hello JCat
It's on the list of possible side effects:
Treatments and drugs - Bicalutamide.
I would contact your team about this / If you can't speak to someone today you need to contact 111 for advice.
Best wishes - Brian.

Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm
Strength, Courage, Faith, Hope, Defiance, VICTORY.
I am a Macmillan volunteer.
Hi Brian
Thankyou, we have contacted our oncology team, dad currently in A&E and is being admitted. Just wondered if anyone else has experienced it as it wasn’t presented to us as a side effect. He hasn’t started any other treatment yet but has fluid on his lungs and a blockage in his kidneys. I’m worried that things seem to be progressing faster than we can manage, we haven’t even had a chance to discuss any treatment plans with the consultant yet.
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2026 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007