PSA rise

  • 1 reply
  • 178 subscribers
  • 35 views

Hi All, my husband has stage 4b, Gleason 10. He got diagnosed last January with a PSA of 186 and after triplet therapy, we got down to 0.03 two months ago. He has PSA tests every month, and last month there was a slight jump to 0.05 which we tried not to worry about. But we’ve just got the PSA result today and it’s 0.1. He does have a slight cold, and has also got a shoulder rotator cuff issue (we had an MRI to rule out any cancer) but I have to admit I’m panicking. We’ll follow up with the oncologist but obviously won’t hear anything over Christmas and I just wondered if anyone has any words of wisdom or advice as to what next steps will likely be. It feels really shitty timing with Christmas and I’m worried this means he’s becoming castrate resistant

  • Hi  , sorry to hear about your husband.  We all panic and worry but sadly it won’t make any difference.  Normally 3 rises or a PSA of 2 trigger a response from the medics but with a clear MRI recently and a very low 0.1, I doubt they will take action but a PSMA PET might pick something up if the PSA goes over 0.2.

    I was always confused about the castrate resistance and assumed that once HT stopped holding the PSA then the game changed.  However, when my PSA started to increase a small metastasis was found.  This was zapped with RT and I am back with the original HT still working.  So in my layman’s terms, the metastatic cancer was the only bit castrate resistant.  
    Try and enjoy Christmas and make some happy memories.

    Best wishes, David

    Please remember that I am not medically trained and the above are my personal views.