Hi everyone any advise please
my brother who is doing really well if you read my earlier posts is really suffering with very bad hot flushes constantly he has spoken to his cancer nurse and she has prescribed Cryproterone .
hrs worried about some of the side effects he’s read
has any one got any information on this drug or has anybody taken it and offer some advise ?
he has tried the sage but no joy
thank you
Bg
I had problems with hot flushes and was prescribed Medroxyprogesterone 10mg tablets 2 once daily .
They proved effective . The course lasted a month . I have been off them two months and the flushes seem to be returning
I gave them a break as I understand they can lead to bone thinning
good luck
Hi Bg65 ,
I haven't tried this drug, so not really of help.
The sage didn't work for me either, so I looked at other things that might, and thought to myself "Nope, taking enough other drugs already."
I decided to put up with the blasted things.
Then my chiropractor said something that made me think, when talking about the issue as he had to deal with a sweat soaked me. I apologised, and he said "Oh, I'd count it as a win."
When I asked him when he had gone bonkers, he explained that he would simply note it as evidence that the drugs were working. I thought about that for a while, because in truth the drugs are simply suppressing the testosterone which is, in turn, starving the cancer.
He is right, though. It is the only real evidence we can have that the drugs are active.
So now, when I have a hot flush, I imagine little cancer cells boiling in their own juices. It is not strictly accurate, but it makes the hot flushes much easier to deal with.
Steve
Changed, but not diminished.
Hi Steve,
It's ironic that your chiropractor should look at it that way, I've been off the HT now for almost a year but the hot flushes are only now beginning to diminish and I have consoled myself with a very similar thought for some months now.
Back in May this year my Testosterone level was quoted as <0.4 and I am still suffering with ED to some degree despite the Tadalafil that I have been taking since May.
All of that goes to point the same way.
Bg65 I wish your brother all the very best.
Rod
Hello Bg65
Here's a link to the NICE guidelines:
bnf.nice.org.uk/drugs/cyproterone-acetate/
Interesting side effects there including leading to diabetes, depression, man boobs and HOT FLUSHES.
However I can't go against medical advice!
Best wishes - Brian.

Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm
Strength, Courage, Faith, Hope, Defiance, VICTORY.
I am a Macmillan volunteer.
Thank you Brian
my brother has decided against taking them he said he doesn’t want to put any more side effects in the mix and I agree with him he said hot flushes will have to be tolerated as it’s all worth it .
thank you for replying and I hope your doing well Brian
BG
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2025 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007