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I was diagnosed with advanced PC in 2021 and told it cannot be cured. Have been on abiraterone since then. At my last appointment I was told that my medical team believed I was in remission. PSA undetectable for over 2 years bloods are all looking good. What does this mean I am confused

  • Hello  and I would say that is great news. There is a good video on this topic.

    https://youtu.be/5Sfub1QpY74?si=YC0XzG3Zp7Eba28V

    Sometimes when you are in remission for a while the experts might consider giving you a holiday from hormone therapy as this is showing that it could prolong the time until recurrence in the future as well as giving you a better quality of life.

  • Hi Brizee

    I agree with AH, Def good news especially as they are talking about remission.

    Also a holiday from the Ab if the specialists agree , reserve for later if needed.

    Best wishes 

    Steve 

  • Sounds like this is great news, I am so pleased for you 

  • That’s brilliant Brizee! My husband is on triplet therapy and round 5 of 6 of docetaxal. We recently had a second opinion appointment at the Royal Marsden who kept talking about the aim of getting the PSA down to NED for 2 years and then taking my husband off hormone treatment. She kept talking about “if” the cancer comes back after that. Whereas our primary oncologist has said my husband will never come off hormone treatment and the cancer will definitely come back at some point. We were really confused and asked about it, and the oncologist at the Royal Marsden said they are starting to do things they never considered were previously possible - like taking someone off hormone therapy after 2 years, and there being a chance that it doesn’t come back. Or as Always Hope says, that it’s a holiday from hormone therapy and then helps with the time to recurrence. If I’m honest, I’m still a bit confused by it but my take on it is that there is hope, and it sounds like you’re in a strong position! Sending love and strength 

  • Hello Anna42,

    I finished the docetaxel stage of triplet therapy last September, now on HT and darolutamide. My consultant said this will be forever or until the cancer comes back, but I have seen a few examples recently where patients are taken off treatment after a couple of PSA undetectable years. Your second opinion on this is indeed encouraging.

    I get the impression that, at this stage, because triplet is relatively new the specialists are still feeling their way. It may well be that we can be given a break after a couple of years if all is otherwise OK and I hope this is the case provided the benefits of doing so outweigh the risks. I guess we'll just have to wait and see.

    I hope your husband's remaining chemo goes well and wish him all the best for successful treatment for many years ahead.

    Derek.

    Made in 1956. Tested to destruction.
  • Hello Anna. There is quite a bit of evidence behind using intermittent hormone therapy but it doesn't seem to be something taken advantage of very much in the UK.

    Have a look at this video.

    https://youtu.be/k92ETEqVYJ4?si=BobVmTiOi5nl1hB7