MRI report

  • 31 replies
  • 185 subscribers
  • 2051 views

Can someone help me understand my husband MRI report please? 

How serious is this please

His PSA is 4.86

But the MRI report seems indicating high grade cancer and almost entire occupy the prostate?? His biopsy is not until the end of the month! so 3 weeks from now!! Waiting is killing!

He is in othewise very good health condition and 67 and his parents recently passed at age 92 and 94 so I am hoping that he inherited the family long life gene!

PROCEDURE: MRI PROSTATE W WO CONTRAST 
 
HISTORY: Elevated PSA. Most recent PSA 4.86 ng/mL on 10/24/2024.  
 
TECHNIQUE: Multi-parametric 3.0 Tesla MRI was performed using a torso phased-array coil, including multiplanar T2-weighted images, axial T1-weighted images, axial diffusion-weighted images, and volumetric dynamic post-contrast images of the prostate. Axial in-and-opposed-phase gradient-echo T1-weighted images and pre- and post-contrast fat-suppressed gradient-echo T1-weighted images of the entire pelvis were also obtained using the "Prostate with Contrast" protocol. 
 
 COMPARISON: None. 
 
 FINDINGS: 
 Prostate size: 4.6 x 3.7 x 3.9 cm for an overall volume of 35 cc. PSA density: 0.14 
 
 Tumor localization: Lesion 1 in the transition zone PI-RADS assessment category: 5, Very high probability Appearance on T2-weighted images: 5, lenticular or non-circumscribed, homogeneous, moderately hypointense, and >1.5 cm in greatest dimension, or definite extraprostatic extension/invasive behavior Appearance on diffusion-weighted images: 5, focal markedly hypointense on ADC and markedly hyperintense on high b-value DWI; >=1.5 cm in greatest dimension, or definite extraprostatic extension/invasive behavior. This lesion has a low ADC value of 0.4 Appearance on dynamic post-contrast images: Positive - focal enhancement directly corresponding to the suspicious finding with early or contemporaneous enhancement to normal prostate 
 
Size: 1.8 x 1.2 cm, series 17 image 14 (T2) 
Side: Right 
Zone: Transition 
Level of prostate: Predominantly mid gland (nearly involving the entirety of the anterior transition zone) 
Location within transverse plane: Anterior 
Extraprostatic extension: Abuts the prostatic capsule 
 
Additional peripheral zone findings: Linear or wedge-areas of decreased signal on T2-weighted imaging with associated diffuse increased perfusion, suggestive of prostatitis. Additional transition zone findings: Enlarged and heterogeneous with circumscribed nodules consistent with benign prostatic hyperplasia. 
 
Extraprostatic extension: None. 
 
Seminal vesicle invasion: None. 
 
Lymph nodes: No pelvic lymphadenopathy. 
 
Osseous structures: No aggressive osseous lesion. 
 
Additional findings: The urinary bladder is unremarkable. There is a 0.6 cm prostatic utricle cyst. 
 
IMPRESSION: * 1.8 x 1.2 cm right anterior predominantly mid gland (nearly involving the entirety of the right anterior transition zone) transition zone lesion, corresponding to an assessment category of PIRADS 5 - Very high (clinically significant cancer is highly likely to be present). This lesion abuts the prostatic capsule with a low ADC values of 0.4 suggestive of a high-grade tumor. 
 
* No lymphadenopathy. 
 
The prostate gland was segmented and the suspicious lesion(s) were annotated on the DynaCAD system for UroNav guidance. 
  • all I know is agreesive high grade

    Hi again.  It may be high grade and PIRADS 5, but this just means they have a really clear MRI image and they can see the lesion. I can’t see the word “aggressive” anywhere, and that’s because the MRI can’t tell what grade the cancer is.  The biopsy will tell you that.  Histology is King, and the biopsy will be the provider of that.  Big lesions can often be low grade, so please don’t go thinking of an aggressive cancer before seeing the histology.   AW

  • Thank you Brian. I appreciate your reply and everyone else on here. I will keep reading. There are lots of valuable information here and really helps!

    Ying

  • Just to add that my understanding is that the phrase "T2" suggests that the cancer is entirely situated within the prostate gland, which gives you ALL the treatments and a probability of a cure.

    However, to be guided on treatment, you will need the results of that biopsy.

    Let's say, for a moment, that your other half has an aggressive cancer, as I do.

    Then the biopsy will define it, and will be the guide, along with other tests ordered that will give a full picture.

    Lastly, I will share with you the thought supplied to me at the time of my biopsy by the cancer nurse specialist attending. He told me that even an aggressive cancer, such as mine, doesn't move as fast as we (untrained people) think. He said "there is time to get it right".

    Breathe in, and move forward.

    Steve

    Steve

    Changed, but not diminished.
  • I want to add some updates.

    My husband had biopsy and result was Gleason 3+4 and T1cN0M0, and the tumor is in transition zone (I am not totally understand different zones but anyway). Together with his PSA 4.8, Doctor thinks it's curable which we are very thankful!

    We are given options of surgery and radiotherapy. And we are taking the surgery option.

    Surgery will be 3/27 and we requested to be the first surgery in the day.

    I also wonder when we should be referred to the oncologist. At this point, the surgeon is sure that the cancer is contained within prostate so he is not having a PET scan. Should we insist to have one? Pray for the final pathology after the surgery remains the same stage or even lower!

    Thank you everyone for replying to my questions and giving us hope. We really appreciate it! Also I updated our profile.

  • Hi, was he offered brachytherapy given the cancer is all inside the prostate,  I have just had it, it was 2 visits, no HRT, and each visit was 1 hour.  No side affects at present 

  • Hi  - you have just had the full post biopsy diagnosis and you have already decided on removal.  Well, the surgeon/ urologist is, not surprisingly, touting for your business (surgeons are the “fighter pilots” of the medical world).  HOWEVER, …your husband is 67 and he’s hoping to live to his 90s.  That’s a long time so you need to consider side effects of surgery very carefully. I would DEFINITELY have a consultation with the oncologist.  makes a good point about brachytherapy- an excellent track record with minimal side effects.  A T1c diagnosis is very early cancer, so have a long think and chat to look at all options. I know It’s tempting to “take it out” (the frightened / emotional response) but please take your time and use the medical consultation process to its full and make your decision based upon all factors.   AW

  • Hello  

    Further to the great post above from  here are two links to our guides to:

    Surgery To Remove The Prostate. and

    Brachytherapy For Prostate Cancer

    I do hope these two links give you a little bit more information on treatments and help you make the correct choice.

    Best wishes - Brian.

    Community Champion badge

    Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm

    Strength, Courage, Faith, Hope, Defiance, VICTORY.

    I am a Macmillan volunteer.

  • Thank you very much! We will definitely look into it! Thanks.