Has anyone had a really bad reaction to either alendronic acid or enzalutamide?

Hi there,

I have been on enzalutamide for nearly 4 years and main side effect for me is fatigue.  Never felt sick on it.  We all react differently but I would suspect the alendronic acid.

Hope thy can sort it out soon and your PSA is nice and low when you get results next week. 

Best of  luck, Steve

Hello. My husband was on Enzalutamide for 18 months and his main side effects were greater fatigue and he became more unsteady on his feet. He is on a different drug to protect his bones - Xgeva and again no gut issues.

I was reading the guidelines for Alendronic acid and see that it recommends taking it 30 minutes before breakfast and to stay upright so I am wondering if taking it in the evening might have precipitated the side effects. These are the NHS guidelines.

www.nhs.uk/.../

Hi Ever hopeful, I have been on alendronic acid a couple of years, I take it first thing in the morning with plenty on water, about a pint, then go for a walk, 10 minutes is enough, and sit upright until a hour has passed before eating/drinking anything else, never had any problems.

Eddie

Hi, just a little add on. alendronic acid takes about 6 months to begin working.

Eddie

Hi Ever hopeful , I have just stopped taking Risedronate Sodium 35mg after 5 years.  I never had any problem but took them first thing with a pint of water and stayed upright for 30mins before eating anything.  5 years is the max time apparently to take the drug.  Coincidentally I have recently started on Enzalutamide 10weeks and have massive fatigue but no other side effects.  David