HT + Enzalutamide, side effects, sleep, etc...

Hi Troxly

I have been offered the Enzalutamide and also am reading about the side effects. I haven't heard anything positive about taking  this treatment so for the time being have suggested we hold back on this path. 

I have though been on monthly injections ( presently being given every 3 months) as I was at the start of my treatment 4 years ago. This has reduced my PSA again and I am feeling quite good. My decision has been to hold off on the Enzalutamide in favour of quality of life. I am 74 now so who knows how much time I have left and prefer to make the most of my current health. Family are off my hands with Grand children I am financially sound and my wife is supportive. All things I have considered.

Incidentally my continuous and frequent sweats are being kept in check with a drug called Medroxyprogesterone acetate 

Best of luck with your choices

Teapot

Hi teapot.

I'm 49.

Been told enzalutamide take 2 weeks come out system, feeling bit better now, sleep still bad but getting some more, but feel bit more like a human 'being'.

ALSO THIS IS JUST MY OWN PERSON EXPERIENCE AND EVERYONE RESPONDS DIFFRENT. ANY BODY READING THIS SHOULDNT LET IT PUT ANYONE OF TRYING IT, 

IT MAYBE THE RIGHT THING FOR YOU AND GIVE YOU GREAT QUALITY WITH LITTLE SIDE EFFECTS.

Felt like signing death warrant coming of the Enzalutamide....

But am feeling better, the injections hopefully keeping me ok at mo.

Got 15 year old twins, 

3 decent years probs be great, boys be 18 and will feel bit more like I've done my guiding role....they young men able grow trendy beards n silly hair cuts.

I try live in this day only, and just for this day(today) life is good

 loss of sleep and extreme lows at times stop me being able to see this, or do the things that help get me out of these.

It's nice to be open and honest...we can all say words and pretend, for me reality can be great tool as well as denial.

Hi Troxly

I have been on HT  & Enzalutamide for 20 months now, like you had a little issue with hot flushes, restless legs, dried skin & sleeping properly as well as heart palpitations, within 3- 4 weeks most these settled down. Still have the dry skin but nothing that aveeno can't sort out. Flushes are few & far between now & living a fully active normal life.

Wish you well on your journey 

Hi I have been on Enzalutimide for 27 months now along with a three monthly hormone injection .I had salvage  RT after failed prostectomy in 2020 and my psa fell from 28  where it rose to after the prostectomy to undetectable four weeks later and there it has remained ever since .I have hot flushes ,difficulty sleeping and restless legs but all side effects are manageable. I use cool gel pads at night which help the restless legs and hot flushes ,I get tired easily but other than that I'm doing very well indeed as the cancer is in remission .Enzalutimide in my case was used as first line treatment as I'm still hormone sensitive and as far as I'm concerned is a wonder drug .The fact my prostate was removed has helped it makes the cancer load less ,the mothership so to speak has been removed so the treatment can be more effective in fact there is an ongoing trial where advanced cancer patients who normally would not have their prostate removed are having them removed and treatment continued to prove the above .Enzalutimide is a remarkable drug for many men who respond to it .