Does Prostap 3 give symptoms a couple of weeks before next jab is due?

Hi

Zytiga can give all the symptoms you’ve mentioned, it is a strong treat that kills the cancer cells, I’m on its counter part enzalutamide when I took the the four tablets daily, it sent my head spinning, thought I was going to have a stroke, after speaking with my oncologist we started again two tablets the three now I’m on four. 
Medication comes with side effects, some people are lucky, I’m not one of those, the prostap will cause fatigue and tiredness but yo get used to that, his body with the Zytiga may just be starting to take affect with the medication, but to be safe I would give the urology dept a ring or his specialist nurse, let them know, even if you cannot speak to anyone, be sure to leave a message their usually quick to reply.

Stay safe

Joe

Thank you Joe… I’m on it now! Going to call them.

feedback later need to get to work thank you for your prompt response. 
louli

I'm on Enzalutamide and Firmagon which is similar. I find as I get to the end of the 4 weekly maintenance jab that some bone pain might return. I think the answer is to give it time. It can be a good 2 to 3 months before the Zytiga or Enzalutamide takes effect. 

With Firmagon its important to check that that nurse has fully dissolved the powder if you're going to get the full effect of the drug over the 4 weeks. Hope that helps.

Arthur  

Hi Louli,

I have been on Zytiga & Prednisolone for 20 months now as my first line treatment, Covid actually helped change my initial treatment plan. I started Prostap3 injections about a month earlier. Every month since I started the HT injections I definitely feel more fatigued, lethargic and my mood dips about 2/3 weeks before I`m due my next Prostap3 injection. I have a few side effects with Zytiga but they are consistent and do not change or vary much at all. It is like setting a timer when my symptoms appear with Prostap3. Hope this helps.

Take care, Tom.   

Hi Louli

You may recall that I responded to your previous post as my diagnosis was very similar to that of your husband but I am about 18 months ahead in terms of my treatment.

I was prescribed Zytiga in August 2020 but was taken off it this year as it was no longer proving effective in suppressing my PSA. It is a hormone treatment which, like Prostrap 3 ( which I have been on for 2 years) reduces testosterone on which the cancer feeds. It is well known that the side effects of Zytiga are more prominent in the early days but these generally wear off with time. It can sometimes cause a slight flare up although I have to say, I did not experience this.

You don't mention what sort of pain your husband is suffering from. I manage my pain with Paracetamol or, if more severe, Co-Codamol, or one of each. I am reluctant to use them regularly as they cause constipation and one can end up feeling even worse! I get good and bad days and it is important to make the most of the good ones.

Thanks Arthur that’s interesting and a useful reference for us.

thanks,

Louli

Thanks Andy, I’m sorry not to reply sooner I don’t know whether I’m coming or going at the moment. 
I do remember you very well! Yes it’s hip, spine, and neck pain exactly where the dr says his mets are. He accidentally overdosed on Xytiga on Hogmanay so had to be watched closely. Apart from tinnitus, bone pain his BP went up slightly but restarted on drs advice on the 3rd. He had an awful time of it. So painful to watch. 

He is exactly the same as you in that he prefers not to take pain killers. He takes 2x 30/500mg cocodamol in the morning and just the odd paracetamol if it’s bad. Just can’t get him to take regular paracetamol!

Hate to see him suffer the brain fog he seems to be having. He is such an intelligent person and get frustrated with himself sometimes.

Thank you,

Louli

Wow! That’s exactly what my husband is experiencing. Currently his Prostap 3 on 17th January so it’s a difficult period. 
So sorry I didn’t reply sooner .. I don’t think my notifications are on. Anyway great to hear from you.

thank you,

Louli

That’s good advice. It’s funny how it’s the simple things that can have the biggest consequences. 
thanks for your kind help Arthur.

louli

I've also found that on the day of my jab with Firmagon I will be completely fatigued by the evening. This can sometimes extend to the day after. So for example I had my jab on Tuesday. It has taken until today Thursday, after a good night's sleep to return to normal. The bone pain has gone however so it must be doing some good.