Morning all,
Quick background summary: stage 3c HGSOC diagnosed Oct 2023, debulking surgery Nov 23, chemo ended April 24, been on Niraparib since May 24, latest NED scan Aug 24. BRCA neg and HRD neg.
I get 4-weekly blood tests due to still being fairly early days on Niraparib. Two weeks ago my CA-125 had shot up to 110, following previous month at 33, and single figures before then. Latest CT scan this month shows early stages of first recurrence in different sites, which is a huge disappointment after such a short time. I see my consultant tomorrow for all the details and a discussion about what happens next. However, I had already spoken to a CNS on the phone on Thursday and asked her to give me the headlines of my results over the phone. She had been in the MDT meeting during which they'd looked at my scan and discussed it. Apparently, if chemo is the decision (carbo/caelyx) then I might be offered the chance to go onto the Gloriosa clinical trial as well. This is fairly newish, I think, and currently open to people with my profile.
So just wondering if any of you have been on it, are on it or had it suggested please? What's your experience?
Here's what I know so far: https://targetovariancancer.org.uk/about-ovarian-cancer/clinical-trials/gloriosa-study-mirvetuximab-soravtansine-and-bevacizumab
Many thanks in advance!
