Third line chemotherapy for ovarian cancer

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Hello, I was diagnosed in Aug 2021 with stage 4a ovarian cancer. I’ve had debulking surgery, two cycles of carboplatin paclitaxel chemotherapy and was on Niraparib for a year. These have stopped working. My cancer has spread to my liver peritoneum and spleen and my oncologist has started me on Caelyx. 

Does anyone have experience of caelyx, and how effective is it on metatastic cancer? i am worried as i know if this doesnt work there doesnt seem to be anything else

thankyou

Di

  •  

    Hi Di

    I'm not a member of this group and don't have any experience with the drug caelyx but I noticed that your post hadn't had any replies yet. Responding to you will 'bump' it back to the top of the discussion list again.

    I used the search function to look for previous posts which mention caelyx and found these for you to have a look through. You could reply to any where you think the poster may be able to help further.

    Wishing you all the best

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  • FormerMember
    FormerMember

    Your team will try out drugs you haven't had before. Ideally you will get a response, either full or partial, to shrink/control the cancer and give you a treatment break for a while. You haven't had gemcitabine either, and then there is weekly taxol. You might also want to look into self funding avastin if you go for weekly taxol. There are other treatments beyond these, plus clinical trials. Don't be too despondent. It's very hard to face the prospect of lots of treatment but there are options. Concentrate on being as well as you can be xxx

  • Dear Bella Bee

    thankyou so much for your positive response. I can’t have taxol anymore..it’s stopped working. I hadn’t thought about self funding Avastin. I’ll ask about that now and Gemcitabine. 
    thankyou xxxx

  • Hello Wave 

    I so hope you find something that works for you Bella Pray Will the NHS in your area not fund Avastin? I'm stage 4 & have Avastin alongside taxol/carbo, and will have it ongoing for maintenance but its freely available to me, I don't pay

    All best wishes xx

  • FormerMember
    FormerMember in reply to Blossom1

    Don't rule out weekly taxol. It sounds like you are platinum resistant, so it's carbo they rule out. Lots of women who recur on carbo taxol go on to have weekly taxol. 

  • FormerMember
    FormerMember in reply to KazWaz

    Unfortunately, Avastin is only available under specific settings, the NICE guidelines state what these are. Many patients therefore self fund it xxx

  • Hi, I'm about to start caelyx for endometrial cancer, which has spread to my liver, spleen and other places. I've stopped responding to carbotaxel and also immunotherapy and hormone therapy didn't touch it. So caelyx was offered as a less harsh option than a doxirubicon combination. My Dr said I wouldn't experience hair loss which is the main reason I agreed to it but this doesn't seem to be the case. How did you find it? X