Hi. I have been diagnosed with stage 3c ovarian cancer. I had de-bulking surgery eight weeks ago where all visible cancer was removed. I am due to start chemo next week. My CA125 was originally over 1000. It then reduced to 254 just prior to my surgery and this week is 39 so almost normal. I know this can be an unreliable marker but that it is used during chemo to measure its efficacy. As it is nearly normal I am wondering if having chemo is worth it due to the risks involved, particularly as my spleen was removed during surgery so I am already immune compromised. I guess it should be a discussion with the oncologist but wondered if anyone else had had the same experience. Thanks.
Hi , sorry to find yourself here, I'm stage 4b as I also had my spleen removed. Personally I would have chemo as it completely kills any microscopic cells that linger and will give you a better chance . I'm thrilled your CA125 has dropped so well, but you now want it to remain they way.
I've just had my first chest infection after cycle 4 , I've been given a strong dose of antibiotics and have recuperated really well.
The best advice is to chat to your Onco and follow their advice.
All the best
Hi thanks for the response. Sorry to read about your infection but glad you are responding well. I have had my first chemo and am on day 7 post it. Have felt pretty awful so far, numb fingertips, heels, severe fatigue in that I can hardly walk sometimes, that may be the filigrastin injections or a combination of those and the chemo. My body feels like it is really numb, is this all usual and does it get any better during the cycle? I really hope so. I had an allergic reaction to the paclitaxel so I was pumped full of steroids. I guess the chemo is doing some good (I would hope) as it is so hard to allow such toxic nonsense to be swimming around. A real dilemma. I have been told I need to have at least four carboplatin to qualify for naripbabib (something like that…) x
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