Stopping immunotherapy due to disease progression

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My husband was diagnosed with Mesothelioma in June 2023.  He started on immunotherapy in August 23 and until January was told  tumour, pleural thickening had shrunk.  Fast forward to April 24 even though most of the nodules have vanished there is one localised area that has doubled in size.  Even though there has been some progression he is still felling well , has no breathlessness & has never had pleural effusion.  He has now been offered Chemo - Pemetrexed & Carboplstin - has anyone else had this for their Meso & how did you get on with it.      

We did ask if there were better treatments available elsewhere but were told that private treatments haven’t gone through trial & most aren’t licensed.  Just wondered what other treatments people are being offered or are currently on - as we are currently feeling deflated & a little shell shocked at the progression since January.            

  • Hi  

    I can understand why you and your husband are feeling deflated but hopefully the pemetrexed and carboplatin combination will help.

    I'm not a member of this forum, and haven't had either of the drugs that have been offered to your husband, but I noticed that your post hadn't had any replies yet. Responding to you will 'bump' it back to the top of the discussion list again.

    While you're waiting for forum members to reply, it would be great if you could put something about your husband's diagnosis and treatment to date into your profile as it really helps others when replying to you and also when looking for someone on a similar pathway. It also means that you don't have to keep repeating yourself. To do this click on your username and then select 'Profile'. You can amend it at any time and if you're not sure what to write you can take a look at mine by clicking on my username.

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  • Thank you - I have completed profile.