Pembro - Should I be scared of side effects or not?

FormerMember
FormerMember
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Hi all,

It's great to have this amazing platform and connect with wonderful people like you - somehow feels like one is less alone in this!

I've recently been diagnosed with Melanoma Stage 3 AA, after finding a minuscule deposit left in a sentinel gland, post biopsy and wide excision on my upper back. My oncologist has mentioned doing Pembrolizumab for a year, every 6 weeks. When she run through the side effects of Pembro, (some of them can be long term and that's what really got me thinking and worrying) I left quite scared and confused... However, once I found a bit more info about this drug online (here in MacMillan and Cancer Research) and after reading a few of your experiences, somehow it feels like those side effects are (or can be) more manageable than I thought. What are your personal experiences with Pembro, in general? I'm 30 years old and in very good health otherwise, so the idea of feeling 'sick' or tired for a whole year is not very comforting! Basically, is Pembro as scary as it seems, or is it actually manageable?

Thank you very much, and wishing you all great health and strength!

Lucia

  • FormerMember
    FormerMember in reply to Amccl

    I am pretty sure the BRAF doesn't matter with Pembro. I think it is important with targeted therapy. Immunotherapy is nothing like chemo. Don't worry. Only a very small percentage of patients have bad side effects and Pembro does help 

  • Many thanks, if you don’t mind me asking did they give you many treatment options to consider ? 

  • FormerMember
    FormerMember in reply to Amccl

    I went to Churchill Oncology Hospital in Oxford. They went through everything that had happened to me and recommended Pembro.  My consultant specialises in Melanoma so I wasn't going to argue. Had researched it before so was comfortable with their choice.

  • Many thanks, I will be meeting with the Glasgow Beatson team next Thursday 

    (I had a  2.5mm on my eyebrow so WLE and SLNB) 2 nodes at my ear were found to contain trace of melanoma. CT scan is clear so adjuvant treatment going forward was all I was told. 

  • FormerMember
    FormerMember in reply to Amccl

    I had a 4.1mm on back of my right hand. Like you 2 nodes in my right armpit but they took out all 29. We are so much better off now than 10 years ago.  Immunotherapy is a game changer. Hope all go weeks for you next Thursday.

  • Thank you for your insight and information. Glad you are keeping well Thumbsup tone1

  • pembro for me too and will Hopefully be starting A week on Monday. 

  • FormerMember
    FormerMember in reply to Amccl

    That's great. I hope it goes as well for you as it has for me. No side effects. Be grateful. It costs the NHS tens of thousands of pounds for a one year treatment.

  • FormerMember
    FormerMember

    Hi, I thought I would update you all! It's been 2-3 months since my first post, and things have changed a lot since – Basically after the scans and MRI, needed to decide whether Pembro was a good option, they couldn't find any trace left in my body, so what they recommended was against Pembro, as there was virtually no need for it. So here I am, 3 months later, I consider myself cancer-free as the doctors mentioned, and going for check ups every 3 months and scans every 6 months. And being super careful in the sun!

    Thanks so much to all of you for your replies and information and shared experiences. I wish you best of health on your journey!

  • FormerMember
    FormerMember in reply to FormerMember

    Pleased for you Lucia.