Immunotherapy and pain

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My 77 year old husband has stage 4 lung cancer and stage 4 prostate cancer. He finished immunotherapy in December 2025. He has had severe pain in his thigh for a year and is currently prescribed mst and paracetamol. The doctors don’t know what is causing the pain.
This medication was managing his pain but is not doing so well now. 
I try to encourage him to exercise and although he will go for a short walk he lies in bed and sleeps till about 2 pm every day if he has no appointments. He does not seem to accept how bad this is for his pain.