Dendritic Cell Therapy (AKA DCVax)

Hi

I cant I'm afraid. That's why I had to go to Germany. I do know that Kings Collge Hosp in London ran a very similar vaccine Trial called DC Vax L.but it closed.

www.cancerresearchuk.org/.../a-trial-of-a-vaccine-called-dcvax-l-for-glioblastoma

https://www.theguardian.com/science/2022/nov/17/im-just-carrying-on-vaccine-gives-brain-cancer-patient-years-of-extra-life

Thanks for sharing this Mat! Great to hear it’s had a positive impact, fingers cross it continues! My dad has just been diagnosed with a high grade glioma ( caught by accident so it’s small and currently symptom free. I want to explore this option you mentioned that’s in Germany. Would you mind chatting me through it by any chance? 

Sure DM me for next week. Currently on hols in Cornwall 

Thank you! Enjoy your trip!

Hi Mat. So great to hear this has worked for you - how encouraging. My father has recently been diagnosed with a very aggressive and large grade iv glioblastoma. We have been looking at immunotherapy - but aren’t sure how quickly it acts / the process length/ whether you can do it after a certain size the tumour has grown too etc - time isn’t something we have right now. Are you able to help at all in terms of sharing a few details around your treatment? Hearing from someone who’s been through the process would be invaluable. 
my father is 70. And obviously the older you are the harder these things hit/ are able to be recovered from. He’s deteriorating by the day and we are desperate to see if there is any hope of a mir for him… thanks so much

Quickly ? I'm not sure. It was done in conjunction with Lomustine. But my improved scan was 3 months later.

The process was two 0ne-day visits to Germany. So you can stay for a week or do a couple of overnight trips. If the tumour is too large, it may be too late for this treatment. The clinic says it works best at an early stage when the tumour is smaller.

I'd recommend contacting them to ask.

Hi Mat, 

thanks for sharing your experience. My cousin was diagnosed with GBM a few months ago, and we are currently looking at treatment options (he is almost done with his first radio/chemo cycle). We heard about DCVax-L, but it sounds like it might take a while to access it (and it's not even clear whether this will happen) + costs are a concern. I have been browsing the website you shared and was wondering if there was any specific publication on glioblastoma by the LDG/any names of specialists working there we could look up? We are evaluating different options now, and the more information we find the more chances we have to make an 'informed' decision. Thanks a lot! 

Nothing specific on GBM, but a Google search on Frank Gansauge + cancer will bring him up.

The cost was 17k Eur plus travel costs each shot. I've had two, but still way cheaper than DCL Vax I've heard. I am not eligible for that as the surgeon didnot keep any tumour samples. So this is a peptide vaccine.

www.cancerresearchuk.org/.../vaccines-to-treat-cancer

thanks a lot for your prompt reply and the link. I might drop them an email and try to find out more. We do have tumour samples so technically he could be eligible, I am just worried about time and money...

sorry, I meant he could be eligible for DCVAx-L