Ribocyclin best time of day to take

Hi MissMolly 

Do you perhaps mean Ribociclib? I don’t have personal experience of this drug but I have looked up MacMillan’s info on it which I link here.

https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/ribociclib

It just says take it at the same time each day. Consistency is important with all drugs. 

Yes I meant Ribociclib. Thanks for the information. I was really wondering whether other users found it better to take in the morning or in the evening

Hi 

I take palbociclib which is slightly different and I take it at bedtime and have never had an issues 

Hi, I have been taking ribociclib for 4 months now. I was advised by my care team to take it in the morning. The reason they gave for this is that it can cause issues with sleep if it’s taken too late. I take it along with letrozole for ER/PR positive, HER2 negative metastasic breast cancer. Good luck with your treatment and I hope all goes well. 

Hi there, I have Stage 4 breast cancer with a met in the lung. I too am on Ribociclib and Letrozole and take both just before breakfast in the morning. Side effects for me include hair thinning and some early morning joint stiffness but otherwise lucky as they haven’t affected my digestive system!!! I have had low neutrophil counts along the way resulting in my Ribociclib dose being altered but still taking it and I’ve just passed my one year cancerversary. 

Thanks for your reply. I have early morning joint pain - takes me a couple of hours to get going !! It didn’t occur to me the drugs could cause that -I assumed it was the cancer. I have fulvestrant injections monthly and due to start denosumab injections for bone strengthening as cancer spread to my bones. It is so helpful and encouraging to talk to others in the same or similar situation. 

Thanks for your reply. I take it in the morning  and so far so good. I have just finished my first three weeks so now on a week off. 

I am also on denosumab as my mets are also in my bones. I find I have joint pain primarily in my knees and fingers. It only causes trouble when getting in or out of a chair or walking up or down stairs or a slope. My fingers do get achy when I drive. I do find that it feels worse after the denosumab injection for a few days but it will pass. Just take it easy for a while. My hair is also thinning. Unfortunately I didn’t have much to start with, so that’s a bit annoying. I do feel nauseous on my 3 weeks of ribociclib and love the free week as I feel much better. Due a CT scan soon, so fingers crossed, it’s worth it and my cancer remains stable. Good luck on your journey.