Diagnosis

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Hello, I had breast cancer and the treatment finished in 2022. I am on anastrozol following lumptectomy and radiotherapy. I moved to another country, where I get checked every year. However, it may be brain fog caused by medication, but I cannot remember exactly what they said about my diagnosis and I would like to get more of an understanding of the jargon. My results were - 11mm grade III.  ER+ve. HER2-ve node -ve.

Pre the operations, the biopsies were quoted as NST grade 2 ER8 PRO. HER2 NEG.

I believe I was in the early stages of cancer, but I am getting a bit confused with the grade III, and believe the other jargon relates to being estrogen driven.

I was told the lympth nodes had not been affected.

If anyone can help me understand, I would be grateful.

Thank you.

  • Hi  

    NST means of no specific type - which is actually the most normal type. 

    The grading is how cells appeared under the microscope with grade 3 meaning they looked very different from normal cells and grade 2 somewhat different. It’s not unusual for the lumpectomy pathology to find cells of a higher grade than found in the biopsy.

    ER8 is highly oestrogen driven. PR0 not progesterone driven and HER2 neg not human growth hormone driven  

    At 11mm and not in your lymph nodes it was indeed an early stage cancer.

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  • Your explanation is greatly appreciated. Thank you.