Abemaciclib causing diarrhoea with sweet or fried food - anyone had this?

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Hi iv been on abemaciclib for 2 weeks having 2 weekly blood tests, I’m going away in may. Only had diahrea a few times but am noticing the diahrea comes more with eating sweet and fried foods, anyone else noticed this, I am looking forward to going on holiday x

  • Hi  

    I’m sorry to read about the side effect you're getting while taking abemaciclib. I haven't had this drug but noticed that your post hadn't had any replies yet. Responding to you will 'bump' it back to the top of the discussion list again.

    I presume you've contacted your hospital team about the diarrhoea it's causing as, although it's a common side effect, this information from Macmillan about it suggests you should speak to your hospital team.

    While you're waiting for replies, it would be great if you could put something about your diagnosis and treatment into your profile as it really helps others when replying to you and also when looking for someone on a similar pathway. It also means that you don't have to keep repeating yourself. To do this click on your username and then select 'Profile'. You can amend it at any time and if you're not sure what to write you can take a look at mine by clicking on my username.

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  • I didn’t notice any particular reaction with fried foods and I eat very few sweet things. Salad, green veg and pulses caused the diarrhoea i had in the first 6 weeks. I can eat these things again, but avoided them for a while. I still cook veg a bit softer than I used to. I’ll be 12 months in at the end of this  month, but have had 22 days off for infections, longest spell being 10 days when I had Covid last summer- worse than previous 2 times of having Covid before I had cancer!

    I notice from post above that you’re having a break, I hope you get settled perhaps on lower dose and manage to have a good holiday! xx