Just wondered if any one has been on dose sense neo adjuvant chemo with EC and pacitaxil?
4 cycles of each every 2 weeks .
had my second pax today and unfortunately had a severe allergic reaction just 10 mins in. Had been fine on the first one . They are going to switch me to Abraxane just wondered how anyone found it and did your cycles remain every 2 weeks?
gutted that the wheel had fallen off again and more delays unfortunately.
Hi,
Yes I had 4 x EC then my first Paclitaxel went fine.
I reacted on the second so they stopped it and sent me home with steroids & anti-histamines to take as pre-med for the next try.
Unfortunately I reacted even quicker the next time so yes they switched me,
When I went to nab-Paclitaxel (Abraxane) my cycles changed to every 3 weeks which is the standard recommended for breast cancer.
I'm due my last infusion next week.
Thanks so much for your reply yes it’s not a pleasant experience is it. So glad you are coming up to your last one . It’s just hard when something knocks the plan off but I guess it certainly can’t be helped . Did you find the alternative ok for side effects compared to pacitaxil?
all the best
Abraxane (nab-paclitaxel) is the same drug as Paclitaxel but carried in a different solution so the effects aren't massively different. I think my allergy may have been caused by the dehydrated alcohol in the solution. I'm allergic to red wine.
I found both versions of the Paclitaxel far easier on tiredness than EC.
On the nab-Paclitaxel I have had no sickness at all, but the bone pain is on a par with standard Pac. I tend to get it start when I have the Filgrastim injections.
Thanks , yes I was way better on my first pax than EC like you so just the bone pain. Yes the additives appear to the common factor for the allergic reaction.
appreciate your reply it is always good to speak to others who have had the same treatment.
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