Tamoxifen before radiotherapy

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4 weeks ago I had a lumpectomy for IDCS and have recovered fairly well from the surgery. The next stage of my treatment is 3 weeks of radiotherapy and tamoxifen for 5 years. I am due to go on a much needed 2 week holiday with my family in a few weeks and my oncologist seems relaxed about me starting radiotherapy when I return from holiday-this will be about 9 weeks post surgery. He has told me I can start taking Tamoxifen before my radiotherapy treatment- has anyone else started taking Tamoxifen before radiotherapy? If so, how did you feel? Many thanks for any advice. I know I shouldn’t question his advice!

  • Hi Bab, 

    I have just logged in as about to change from anastrozole to tamoxifen, unfortunately cannot tell you side effects. I started anastrozole before lumpectomy and radiotherapy. Therefore I am assuming you can start before the radiotherapy. I trust my surgeon and am quite sure it is fine. 
    enjoy your holiday xx

  • Hello. I had surgery last June, started Tamoxifen in mid July and had my rads late aug/sept. Theres details in my profile. I started taking it in a morning but had a few days of feeling quite nauseous so switched to an evening after dinner which is much better. Everyone is different so it may be a case of playing around with both time of day and the brand as side effects seem to be quite personal. Have a read of this thread which may help:

    community.macmillan.org.uk/.../oestrogen-reducing-medications

  • Thank you Wajdi. Good luck in your change to Tamoxifen.

  • Thank you so much Tired Minion. Your story is very muck like mine. I hope you are doing well.

  • I stated tamoxifen before radiotherapy because I had an infected wound so they could not start radiotherapy until the wound had healed. 
    It is normal to start it before radiotherapy. 
    hope this helps 

  • I found tamoxifen fine. I don't have any symptoms beyond menopausal ones that I had anyway from the chemo. No joint pains, headaches, nausea or anything like I hear about with AIs. It really has been fine. Also find sage tea helps with my hot flushes/night sweats - I have some nights with only one night sweat and others with loads - though it does seem to relate to whether I had more than one cup of coffee in the day or not. I try to avoid too much caffeine, spicy food, alcohol and sugary foods as they all make the sweats/flushes worse. Enjoy that much needed holiday!

  • Hi Bab 

    I’ve just had lumpectomy 2 weeks ago and was given tamoxifen yesterday. So starting tonight. I haven’t got a date yet for radium treatment. But was told should be in 6 weeks. Hopefully they aren’t too bad x