Letrozole

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Hi. I am due to start letrozole this week/next week (was told 3-4 weeks after finishing chemo so opting for the sooner date!). 

Just wondering, do most of you take it morning or evening? Mixed info online regarding this just that it must be the same time every day really. 

Also, daft question you might think but I am beyond paranoid so want to do everything “by the book”. If you had the vitamin d and calcium supplement did you take that tablet first or the letrozole tablet?

Thank you ladies xx 

  • Hi  , I’m on Anastrozole, older cousin of letrozole! Similar effects. I wasn’t given any instructions re taking it but decided to go for first thing in the morning, mainly so that I’d remember. It’s now so engrained (nearly 7 years) that it’s just what I do. I also reckoned that it would be easier as I’m awake more or less the same time each morning and generally in the same place, whereas mealtimes can be variable and I initially took it with my breakfast in case it gave me nausea (it doesn’t so I now take it on waking and have water beside my bed so I can take it straight away). But that’s all just personal preference. 
    Re the calcium and Vitamin D, I take that with my evening meal, as mine are to be taken with food, so they are around 12 hours apart. I can’t remember why I did this though! Not from any advice. Seems to work ok! 
    Good luck with it, it feels daunting but for me it’s now just part of my daily life. Love and hugs, HFxx

    HappyFeet1 xx
    Don’t be afraid to cry. It will free your mind of sorrowful thoughts. – Hopi
  • Thanks so much for your tips. It is daunting at first, don’t want to forget, don’t want to be out and miss it so first thing is probably the best time actually. Good to hear 7 years on you are still remembering to take it! 

  • Hi, I take mine in the evening, I wanted to ensure any side effects were minimised by sleep and I take all tablets altogether, literally. Best wishes 

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  • And I take mine just after my lunch!! The time can vary between 12 and 1.30 pm - I'm hoping that this doesn't matter.

    I forgot to take my tablet on 2 different occasions and got really worried. I'm now keen to stick to the lunch time routine because it gives me the rest of the day to remember, should I ever forget again.

    I use a tablet organiser / pill box for my Letrozole and have stuck day stickers on the inside of the lids and leave the lids open once I've taken the tablet. This way I can easily check to see if todays lid is open.

    Thankfully I haven't had many side effects - I've been taking Letrozole for 9 months now- so I have stuck to the same brand. It's quite hard work trying to track down my preferred brand every 2 months, but so far so good.

    sx

  • Thank you. That’s a good idea re the pill box, I might do this. 

  • My consultant suggested I take mine at night as there were reports of fewer side-effects, so I've been doing that for the past four years. Having said that, I find increasingly I'm falling asleep on the sofa, so some nights take it a lot later (ie when I wake up). My plan is to take it about 10pm. I take it with other tablets (Venlafaxine to offset the side-effects and Fexofenadine as I have incredibly itchy skin and allergies, plus now Vit D/Calcium supplement). I find it easier to take all meds at the same time.