Vesta AI system for bladder cancer diagnostics, prognosis and treatment plan

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I don't know if this AI system is used in the UK, but I have a Zoom meeting with my surgeon here in Florida on Wednesday to discuss the Vesta results. It is ostensibly used to determine the suitability of BCG treatment, but can provide much more information, such as prognosis for recurrence and invasion into the muscle. Fingers crossed!!

  • Hi MacLean,

    Not heard of this personally, but wishing you all the best for Wednesday.

    Trevor 

  • Thank you, Trevor. I'll report back on the results.

  • Hi Maclean57, 

    I haven't heard of the Vesta AI system, but it sounds very interesting! Best wishes for Wednesday. We will look forward to your feedback.

    Love Ade xx

  • Hi Maclean, that sounds very interesting. I wish you all the best and look forward to hearing how it went. Take care

    Much love Angela x

  • That would really be a game changer, to be able to predict who will benefit from BCG and who not. Be interested to hear more.

  • Had Zoom meeting with surgeon this morning.

    Tumour pTa CIS, high grade.

    Vesta report says because of the presence of a biomarker(?), BCG is unsuitable, so I will be having once a week for six weeks Gemcetabine+Docetaxel directly into my bladder. First treatment 16 October. Vesta also gives probabilities for recurrence and for progression, but I have asked if the numbers are with or without treatment, as it is not clear in the report. Vesta derives its data from many cancer centres worldwide.

  • Interesting, although never heard of "biomarker" on here before.

    Sound's like AI is making it's way into many things.

    I did Google it and apparently it is used in the UK, but never heard of it until now, so must be quite new or rare.

    Thanks for the update.

    Trevor 

  • This what I found:

    What Vesta Means by “Biomarker”
    Vesta uses AI to analyze digital pathology slides and extract subtle patterns that act as prognostic or predictive biomarkers. These are not traditional molecular markers (like FGFR3 or PD-L1), but rather image-based features such as:
    • Cell architecture
    • Nuclear shape and texture
    • Spatial arrangement of tumor cells
    • Presence of inflammation or stromal patterns
    These features are correlated with clinical outcomes using machine learning models trained on large datasets.

  • Hi duraxat,

    As I mentioned above, Vesta determined that BCG treatment is not for me, so I will be having chemo,  beginning 16 October.

    Regards