Parent age 81 not wanting diagnosis

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Hello. My father who is 81 has had some initial tests but doesn’t want to go forward to have the biopsy needed for diagnosis. He is already in severe pain. The family would like him to have a treatment already offered to reduce the pain but this has been rejected so far. I think could be a case of denial or lack of knowledge due to memory issues. We are assuming that without treatment the pain and complications will become unmanageable at some point. Even if surgery  is refused is a diagnosis needed for any further other treatment? Any advice gratefully received to help in overcoming this apparent denial. We have Power of Attorney available to us but not sure what to do as we can’t force some one to have a biopsy against their will. Give that the pain  is so severe  we  feel really don’t feel comfortable waiting for a change of heart on this esp as the treatment offered so far would help the pain and probably memory issues also.
Thank you in advance for any suggestions of approaches that might help.