Adverse reaction to Paclitaxel

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I had my first Paclitaxel and Carboplatin chemo back in June 2024, I was fine after the first session, no problems really apart from bit of hair loss despite having the cool cap.  However, 3 weeks later when I had my second treatment as soon as I was connected to Paclitaxel I have developed a strong allergic reaction - it started with strong back pain moving to my chest and my face went bright read - so the nurse said.  I was disconnected straight away and felt really cold all over.  The nurses made sure my blood pressure and temperature were ok before they send me home.  I was told to come back next day for the Carboplatin only.  I have three more sessions of Carboplatin left.  Just wonder if anybody else had similar reaction?

  • Hi. Yes I had a reaction like that on my 2nd treatment with taxal/carboplatin. It felt like anaphylactic shock and I thought I was dying. It took them ages to come and sort me out. My back was in agony, I couldn't breathe and my eyesight was blurry. This was back in 2021. They flushed some steroids through and then started the infusion again more slowly. I went on to have 2 more taxal combo treatments and 4 more carboplatin only.3 years later my cancer is progressing again. They have mentioned taxal. I said no thankyou! I am either going on a clinical trial or back on carboplatin that I can tolerate well.

  • Hi, thanks a lot.  I have 3 more sessions planned beginning next week but hopefully it will be carboplatin only, don't want to repeat this horrible experience.  I will be assessed  again in October so see if it has worked.  Take care and will be in touch.