LVSI and lymth glands

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My mri showed my lymth glands all looked normal and not enlarged 

what  is LVSI found after histology even if normal before ? 

What  is it please as now worried as my mri  showed ok

 And I did not need anything done with them in my hysterectomy ? 

Thankyou 

  • H mollysue, jane2511 explained this wonderfully on this forum for someone else a few days ago. She said “LVSI means that some tiny cancer cells were found in the vessels leading from the cancer, it has not spread and has not got to the lymph nodes. It normally means further treatment as the potential is for these cells to travel through the blood/lymphatic system and in some people, if not dealt with via the immune system there is the chance that in time, in some people, set up elsewhere and given time could mean a cancer grows. The cells are so tiny that they can not be seen on scans while they are so small. LVSI stands for lymphatic, vascular invasion. The cancer has not spread but it is thinking about it- was how it was explained to me. ”

  • So this is also checked on histology 

  • Yes it’s checked on histology. Any treatment (or not) for this would be decided by the person’s own medical team taking all individual factors into consideration - none of us could or should speculate on what may or may not be the right treatment plan for anyone. 

  • It's very worrying after a hysterectomy isn't it really as although you are staged and graded this can change after op but I suppose it gives a good accurate  idea from a contrast  mri and how to treat 

    it was stage 1a grade 1 originally  and  was told by gyno no chemo at this sTage but maybe radiation to zap it  would be needed but then I read  about lynth glands and LVSI etc which I didn't know about can be found and that concerns me as not many people seem to get same stage and grade as previously advised I do my lynth nodes were normal pre op on her and my ovaries and tubes all normal 

  • Actually as far as I’m aware most people’s stay the same - the predictions are designed to be as accurate as they can possibly be from the outside - finding anything unexpected in the bagging area is the exception rather than the rule! 

  • Hi mollysue

    An MRI would be able to see if your lymph glands were enlarged. They weren't.

    An MRI normally seems to give an accurate picture of what is happening inside your body. That is why they do them.

    LVSI means that tiny cancer cells have been found in the blood/lymphatic vessels. The cancer has not reached the lymph nodes.

    LVSI can not be seen on MRI or CT scans as they are microscopic. They can not be predicted. 

    Most provisional stages and grades seem to be fairly accurate. There can be sometimes slight changes and this is because the post op pathology looks at everything in more detail. Occasionally after surgery they can find something unexpected- but this is the exception rather than the rule. The oncologists view these scans and results regularly and are very experienced. 

    Radiotherapy and Chemotherapy can be needed as a further treatment in some people but they do look at the full picture and then it is still a personal choice to make. I have had both treatments and both are doable. No one wants further treatment after going through something as big as cancer surgery, but they would only suggest it if the benefits would far out weigh the risks. Some people do indeed have no further treatment after surgery but until the detailed pathology comes back - they can't confirm it. With a biopsy they only take a small amount of tissue to test so it gives some basic information. With the scans it shows where the cancer is and whether it has set up elsewhere. During the surgery everything that is removed is tested and therefore they have a much clearer picture. 

    Hope this helps

    Jane

           

    Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm

  • I know they Do blood tests after surgery so Do they do find this  Lsvi in the blood tests then 

  • mollysue what’s removed in the hysterectomy goes off to the lab and is examined in detail under the microscope and that’s how they check, not via a blood test.