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Hi all , just finished 4 rounds EC last one on 11th nov , due to start Paclitaxel next Friday. In the meantime on Tuesday temperature went up so have been In Hospital since with neutropenic sepsis, hoping to go home tomorrow ? 
my question is , my EC was every three weeks , my Paclitaxel is every week for 12weeks I am concerned about managing this next phase in light of the sepsis . I will talk to my doctor on Tuesday but was interested in others experiences ? 

appreciate anyone’s thoughts if you have any ? Thanks

  • Hi

    I'm sorry to read that you've recently ended up in hospital and hope you'll be able to go home tomorrow.

    I had 3 rounds of EC and will have my last of 12 weekly Paclitaxel this week. I've personally found Pax easier than EC. With EC I didn't feel completely normal for about 12 days but with Pax, apart from feeling a little tired the following day, I've been fine.

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  • I think Paclitaxel is less likely to cause a huge drop in your neutrophils than EC did. During EC, it’s usual to prescribe colony growth stimulator such as Filgrastim to help your body manufacture white blood cells, whereas you probably won’t be prescribed any during Paclitaxel (other than perhaps the first time through). That said, my only hospitalisation was when I started Paclitaxel, but it wasn’t due to neutropenia. During Paclitaxel you will have weekly blood tests, so they will be able to keep a close watch on your neutrophils. 

  • Yes, I've been having weekly blood tests but no Filgrastim.

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  • Hi hope all is progressing well for you , thanks for the reply . I will add it to my list of questions for tomorrow . I had no filgrastim until I was neutropenic during EC went down to 0.3 . I just want to makel as sure as possible that i see it coming next time if it does . 
    thanks 

  • Good to hear you found pax easier than EC . Thanks for your reply and I hope things are going well for you ?x 

  • Hi

    I don't like to tempt fate but yes, everything's going well thanks. I had a lumpectomy back in April and having my last chemo on Thursday. Then in about 4 weeks time I'll be having 10 days of radiotherapy. Hopefully that will be all the treatment finished. I do have to have 6 monthly infusions of Zometa for 5 years and hopefully that will go okay too.

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