Hi all — looking for some perspective.
I’m 41, no family history of prostate cancer, no urinary symptoms, no symptoms of anything. I recently had a PSA test and it came back at 6.1 (lab reference range 0–2.5).
I went in for a "well mans" test where my bloods are checked against a few different matrix, all okay. The nurse offered the PSA test and I just accepted with out a second thought so this has come as a complete suprise, I'm blindsided.
I read that your not supposed to ejaculate 48 hours before the test other sources say 3-5 days, I wasn't aware of this. My wife and I fooled around Sunday night and my test was Wednesday morning. Could this have had an impact on the results?
The lab note mentioned the “grey zone” (2–10) and free PSA ratios, but I wasn’t given a free PSA result — just total PSA.
Naturally I’m anxious. I've got an appointment with a nurse practitioner next week but they haven't said what this will entail, assuming it's going to be an interesting one as the receptionist said It needs to be with a male member of the team.
Has anyone else had a PSA in this range at a similar age that turned out to be temporary/inflammation related? Trying to stay calm while waiting for the repeat test.
Thanks in advance.
Hello RunFlat
A warm welcome to the group - although I am so sorry to find you here.
To me the simple answer would be a PSA retest when you have had no exercise or “fooling around- or sex” in the previous 48 hours.
Why you need to see a male member of staff is a strange one. My DRE (finger up the bum!) was done by a lady GP and I have had a catheter fitted and changed by ladies!!
I think I would be asking for a new PSA test before any further intervention- you are only 41 so hopefully it will show a much lower figure.
I hope this helps.
Best wishes - Brian.

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My PSA just went down from 13.2 to 10.5.
13.2 was the initial PSA that resulted in an MRI and biopsy. 10.5 Is the first PSA test of active surveillance.
i went to the GP on another matter and got several tests done. PSA being one. I had no knowledge of requirements before the test. Thinking back I did exercise the day before the test. STRAVA had a 10k in around 55mins. Plus some strides.
Exercise especially cycling can increase PSA so this time no exercise 48 hours before the test. Only difference I can think of.
Hi RunFlat,
From my experience, if an initial PSA test is on the high side they like to have a 2nd one done a little while after just to check the first one wasn't an anomaly. If they are going to do the finger test at the same appointment make sure they take the blood sample first.
As others have said, avoid sex / vigorous exercise for at least 48 hours beforehand.
Best Wishes
Brian
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