Locally Advanced Prostate Cancer T3 (N1, M0) Advise

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Hi Every One,

My name is Grigor ( Age 55) i was diagnosed with T3 (N1, M0) (Gleason score 4+5= 9 ) prostate cancer on 30th December 2021 initially PSA 88.6 which has now dropped to 9.2 after 6 weeks on hormone injections.

It would be great if i could get everyone's views on the following options/discussions i have had with my Urologist.

He has recommended the following treatments as i am young and fit enough - Radiotherapy ( Approx. 4 weeks treatment with hormone treatment for up to 3 years ) or Prostatectomy Surgery to remove prostate, lymph node and tissue around prostate.

I was veering down the road of surgery till my last discussion with urologist who implied/mentioned the higher risk of the surgery ( as more complicated than just prostate removal )  and potentially will still have to have radiotherapy if the cancer has not been totally removed. ( and why would i put my self through 2 major procedures as seemingly both will have the same outcome.) ( my initial thoughts is if i had the surgery which didn't get all the cancer i then can get radiotherapy ??)

I have a appointment with the surgeon to discuss the Prostatectomy ( They will also asses if the surgery is the way forward/implications/success etc )( if they agree to carry out the surgery) and i have to ask them what the benefits the surgery is over the Radiotherapy with all the risks involved.

All your thoughts/input/advise would be greatly appreciated.

Thanks

Grigor

  • Hi Grigor

    Best to stick to 1 post per query, if u go back to your original post u will see a couple of replies

    Steve

  • Hi grigor 

    my situation is somewhat similar to yours . Only thing I had 6 cycles of chemo along with Hormone injections. And psa down to about 4 . Not sure if you had any along with hormone ? 
    I am 49 and although only one surgeon in private sector has offered surgery & others RT . Same as you surgery has to be followed by RT but if RT it’s the one treatment alone at high dose . Surgery the arguments for is - reduce the size of tumor and in case recurrence the complications of surgery are worse like colostomy etc so do it before he says . Oncologist says that’s an old argument bcos RT nowadays is very targeted and curative and chances of reccurence are less and there are lot of meds to treat it . I suppose the only thing that moved me towards RT is this . Already the HT & chemo has dealt with the tumor & nodes and made it small & sanitised and if surgery is done in that area blood spread will be more ( u can’t avoid bleeding in that area ) and will make a lymph node spread into a blood spread which is far worse and spread will go sit in the lung or liver with a far worse prognosis. Again this is just me thinking & how I opted for RT . Hope this helps 

  • With a T3b tumour, I think radiotherapy has the edge, but not by much. You need to look at the side effect profiles of both - especially long term effects - to see which you'd find easiest to live with.

    Also, you should see the oncologist about the radiotherapy, not just hear about it from a surgeon!

    - - -

    Heinous

    If I can't beat this, I'm going for the draw.

    Meanwhile, my priority is to live while I have the option.