Hormone therapy and PSA before radiotherapy?

It’s difficult to say after a couple of months. If he’s on Prostap or a similar hormone, it should decrease testosterone and therefore PSA levels. However, when a man has the first injection, there is a ‘tumour flare’ response, whereby the testosterone surges. This is why tablets are very often given before/alongside the first injection - to counteract the effect. So a blood test now may reflect that, depending on the individual. If the results are high/similar now, I would say not to worry, it will be the next few months when the doctors can build a trend, which you would want to see going downwards. 
Hope that helps! 

When I started HT in October 2018 my GP said I shouldn't have a PSA test for at least 3 months as the results would be meaningless. Having a PSA of 15 then, it had dropped to 0.4 by the time I started RT in mid-February 2019.

It's now 18 months since my last hormone injection and my latest PSA result (received this morning by phoning the Urology dept) was 0.2. So still in remission at the moment.

Thank you.  He had 28 days of tablets and half way through started the injections.  Time will tell

Thank you Seamus. Could you tell me what the PSA is expected to drop to after RT and what 

Good Afternoon All

I started hormone injections in January 2022 (Decapeptyl 22.5mg every 6 months) and have had 2 so far- number 3 is next week. I also had 28 days worth of pills to stop the original flair up but can't for the life of me remember their name!!

In January 2022 my PSA was 182 - about 2 months ago it was down to 1.78. I have had my radiotherapy screening this week and start my 20 days on 5 January 2023 so all is well at present on my journey.

Merry Christmas to All - Regards - Brian.

It’s usually Cyproterone, Bicutamide or Abiraterone. (18 years of my 24 in the NHS was in pharmacy!) 

Bicutamide - That was the one. Old age it's no good!!

Hope all is well in the AM123 household and progress is being made.

Kind Regards - Brian.

Over the time he has HT the trend should go downwards or stay constant as mine did as I came to the mid point of HT - I was on HT for 9 months, and started RT at the 6 month point and had RT for 4 weeks.  The next test it had gone down a little and then continued to do so.  My first PSA test after RT - at 3 months after finishing was what they term undetectable 0.00 something and from then it has stayed pretty constant for the last 6+ years.  I am due my annual PSA test next month - thanks for reminding me that I need to book that test as soon as I can.

It should eventually find its nadir at about 3 - 6 months after completion of RT - though if you continue on HT after RT it won't until HT is finished - I was on HT for 9 months starting RT at the 6 month.  Others are on HT for 2 or maybe 3 years so the lowest point of PSA will not be found until the HT has cleared the body in the months after finishing HT

Thanks Freefaller. The prostate nurse said he would need the ht for 2-3 years and Rt for 7.5 weeks. When we saw the oncologist it was hot for 6 months and 4 weeks rt half way through. He goes for RT planning next Friday. I am wondering what the clinical indicators are for the length of HT and if there are any greater risks of recurrence if it is for just 6 months rather than 2-3 years? Do you or does anybody know? When we queried it the oncologist just said that it’s a matter of weighing up the risks of ht versus the risk of recurrence and my husband could stay on it longer if he wishes!