Zoladex injections

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I'm on monthly Zoldex injections and I'm on them until November 28 I had radiotherapy october 25 sice diagnosis i have gained 8 kgs .I used to be fit and thought nothing of a 7 mile run or 19 mile run now I'm lucky if I can do 2mile my sleep is horrendous I tend to sleep in blocks of 2 hours whilst coping with hot sweats .I was wondering has anyone suffered with lower back pain like a stiffness when getting up or bending down I can't remember my back being like this post prostate cancer ,the brain fog seems to be getting worse and one last question does the weight gain carry on throughout your hormone treatment or does it settle down ,thankyou 

  • I started Zoladex injections in February 2025, followed by targeted radiotherapy in November 2025. 3 months late, as my hospital forgot about me- Macmillan helped out with a letter to the cancer centre. Zoladex continued until April 2026, when my PSA dropped from 29 in December 2024 to 0.03 and, 4 weeks later, to 0.01. It was stopped on the advice of an Oncologist because of the effects on me.

    After starting Zoladex, the first 3 months were fine. After this, I had hip pain, back pain, and shoulder pain. Then ankle pain that caused me to fall twice. I suppose I'm pleased the hospital forgot me, as I could not walk properly because of the back pain.

    By the time the radiotherapy was due, I had recovered a lot; by the 16th session, my walking deteriorated. I got over the radiotherapy quite well for a person in my eighties, with no bruising and hardly any bleeding. However, walking still wasn't good, and back pain returned, and  I was quite breathless. Thanks to the Oncologist at the Cancer Centre, the dreaded Zoladex ended, though it stopped the cancer at stage 3a, breaking out of the prostate at 3b- I was stupid not to get a PSA blood test earlier.

    Now I await an appointment from the hospital, which hasn't turned up after 18 weeks. Also, on returning to the hospital, the oncologist there disagreed with the oncologist at the Cancer Centre. A letter from 12 weeks ago appeared to show that the oncologist at the Cancer Centre won the day.

    I reduced the food I eat as my weight increased and noted that an oncologist at PCRI.org advised having two meals a day instead of three. It was still a struggle, and I remain mainly on a plant-based diet.

    I wish you well on your journey as I wait in hope that the cancer doesn't return.