Apalutamide Side Effects

Hi Greg

I was started on Apalutamide in May this year by my Oncologist after my Prostate Cancer  of six years now had spread to several other places.in the meeting in May she prescribed me with Zomorph am/pm and said its for the pain.

One of the places my cancer has spread to is my spine, she also prescribed oromorpth in-between the zomorpth incase I needed more in the day.

I do get painful legs but nothing to bad obviously due to the above pain relief.

It is probably worth mentioning to your team /oncologist as I also have pregabalin  which is to kill nerve pain, therefore is the zomorph there to relieve leg pain from Apalutamide.

My onco prescribed Zomorph at the same time as Apalutamide  it is therefore worth chasing this up, it costs  nothing to ask the question

Good luck with this, take care Greg

Spud

"you don't know how Strong you are 

until being Strong is your only choice "

Bob Marley quote 

Thank you Spud for your reply, it's much appreciated.

Seems like the pain and Apalutamide are related and I need to speak with my onco as I can't take this pain for much longer.  I can barely walk at times.

Thanks again,

Greg

It’s hard for all of us to differentiate between any pain or discomfort caused by PC,the treatment or a totally unrelated issue.

I have been on Apalutamide for over 3 years and Pregabalin for 12 months.

The Pregabalin was prescribed due to a developing discomfort and pain in the anal region and after tests to show that there were none of the usual culprits such as pile,fissures or anything more sinister.

So the possibility of some neural issue was the prescribed Pregabalan and it does seem to have helped.

If you take away the PC and medication your symptoms sound typical of sciatica which I have endured long before my PC came on the scene and it was really painful and debilitating.Osteopathy cured mine I am very glad to say plus a week in bed and crawling to the loo on hands and knees.

Could your pain be a totally unrelated issue and if so I hope you find suitable treatment.

Rivelin754583 said:

Could your pain be a totally unrelated issue and if so I hope you find suitable treatment.

A very good point.  I've been totally concentrated on my PC and meds when this might not be the issue at all.

Thank you for opening my eyes.

Greg

Get your back pain assessed as a separate issue, in case.

I have had back problems off and on for many years.

When I was having RT for PC the sitting around set it off good and proper, especially the 2 4-hour incidents when one of the machines went off on its own.

I had 2 MRI’s (1 private) to be really sure that it wasn’t the cancer causing it. It wasn’t.

I have spinal stenosis, another charming little condition that comes on with age. It, like arthritis, won’t got away.

So, you can have other problems. Your GP should help you explore what it might be.

In the end, I brought my problem under control by walking when I was able. Yesterday I walked 10km.

The pain never actually went away BUT it has reduced to the level that is barely remarkable.

Explore what you need to, it will set your mind at rest.