Abibiterone

As far as my reading has taken me, not all men become castrate resistant.

Although the comparison is a bit flawed, I have begun to think of the process like dealing with wildfires - much in the news at the moment.

First, you bring the fire under control. Stop it spreading.

Second, you put it out where it is.

Third, you hang around, possibly for a long time, looking for hotspots.

In PC terms this is lifelong, even if you get signed off.

My reading suggests that you keep on with the HT even if you are becoming castrate resistant. One article I read suggested that not all the cancer cells become resistant and, indeed, it may be only some sites. There are all sorts of things that can be done, many only coming online now.

So, I am going to try not to worry about it, and let the firemen cope with the wildfire, which, in my stage, involves my firemen wandering around looking at things with some suspicion.

I’ve just started my metastatic journey and I’m hoping my initial cocktail of meds will not become resistant for a decade, then I’ll have another cocktail and the clock resets, then something in the research and development pipeline allows me to pass away of something else other than this horrible disease. You have to think like that. Best wishes 

Great analogy and my thoughts exactly  

It’s a bit like the plan with me although being a “biochemical recurrence” we can’t find where the little bastards are hiding.

So this is the second time I have stopped HT and yes my PSA is rising again, but as soon as I go back on HT - it drops BUT the little sods can’t get the hang of the treatment and become resistant.

We are trying to confuse them - but at the same time as my oncologist says - I am odd with an initial PSA of 182, no spread but not curable.

Life is good, in my case a challenge but as Sads said above - with a bit of luck in 30 years on my 100th birthday something else will get me!! 

Best wishes - Brian.

Thanks  I will add all this to my thought  locker