Psa test 6 months after radiotherapy

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July 24th 2026 Greg’s first psa after radiotherapy and it’s 2.0 which sent me into a panic, his last prostap was January 1st.  I expected it to be 0. Something.  Spoke to the nurse and she said it’s not unusual and they’ll retest in 8 weeks and she would be surprised if it doesn’t drop more.  Trying to stay positive, but I was really hoping for it to be lower.  It’s strange how normal life resumes and then these tests seem to completely take me off my feet again. 

  • Hello  

    Worry not - it's more than likely "PSA Bounce" after radiotherapy. 

    Radiotherapy keeps on working long after he's completed his fractions. The immune system will still be ditching broken dead cells which have a PSA content and his prostate will still be inflamed.

    It should be lower on his next PSA test and he should reach his nadir or lowest PSA reading 18 months after his radiotherapy was completed and this should be his new base line.

    I can tell you some of us would love a PSA of 2 Innocent but seriously it's fine. 

    I hope this helps.

    Best wishes - Brian.

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  • Hi ww 78

    I don't think after Radiotherapy zero is necessarily expected.unlike after surgery .

    I know that mine wasn't.

    2 is ok, fingers crossed it continues a downward trend, mine did go down for some considerable time after.

    Best wishes 

    Steve 

  • Hello ,

    This link to a Macmillan document might also be useful for you to read. As others say, PSA bounce is the likely explanation, so don't panic. Things don't tend to happen quickly in this game where trends, rather than one-off results, are more important.

    https://www.macmillan.org.uk/cancer-information-and-support/prostate-cancer/follow-up-after-treatment-for-prostate-cancer

    The most relevant paragraph in it is:

    External beam radiotherapy or brachytherapy

    • If you have external beam radiotherapy or brachytherapy, your PSA level drops more slowly. It may take 6 months to a few years to reach its lowest level. Sometimes there is a temporary rise in the first 2 years after radiotherapy or brachytherapy. This is called a PSA bounce. Usually, your PSA level will fall the next time it is checked.

    Made in 1956. Tested to destruction.

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