Hi, I started Prostap 3 just 6 weeks ago. I was told it was quite a mild treatment which wouldn’t make me particularly unwell. But the whole 6 weeks have been almost total fatigue and sever night sweats - bedding changes daily! Does this last all 3 months, or does it get any better - because right now I feel I’ve got not much quality of life between sleeping half the day and sweating all night. This is not what I was expecting. Does it get better? Anyone help please?
Hi TamHutch , sorry you have joined the club. Everyone is different in how they respond to various treatments. HT can be quite severe with some people and others almost have no effect. I don’t know anything about you, but exercise seems to be the main antidote for fatigue, although there is a balance and you mustn’t overdo things. Listen to your body. If exercise doesn’t help, then report it to your team and maybe another HT can be tried.
Best wishes, David
Please remember that I am not medically trained and the above are my personal views.
The hot flushes do often reduce in intensity/frequency when your body has got used to the hormone therapy, but might still be significant. There are a few medications your oncologist can prescribe to reduce and possibly stop them; Cyproterone, Medroxyprogresterone, or Megestrol. They all require blood tests to make sure your liver is coping OK,
Exercise should be considered mandatory while on hormone therapy, and might be available on prescription locally - ask your clinical nurse specialist or support worker. This will help with many of the hormone therapy side effects (particularly fatigue), although not hot flushes. Even if no formal exercise programme is available in your area, walking is one of the best exercises, and thats infinitely adjustable in intensity and duration as your fitness improves.
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2026 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007